Hepatocellular carcinoma (HCC) is the fifth most common cancer and the third leading
cause of cancer death worldwide. Despite recent advances in the diagnosis and treatment of …

The inflammatory tumor microenvironment has been known to be closely connected to all
stages of cancer development, including initiation, promotion, and progression. Systemic …

Hepatitis C virus (HCV) uniquely requires the liver-specific microRNA-122 for replication, yet
global effects on endogenous miRNA targets during infection are unexplored. Here, high …

Background Ferroptosis is a newly identified type of programmed cell death, which
preferentially targets iron-rich cancer cells such as hepatocellular carcinoma (HCC). Ferritin …

How fully differentiated cells that experience carcinogenic insults become proliferative
cancer progenitors that acquire multiple initiating mutations is not clear. This question is of …

Nonalcoholic fatty liver disease (NAFLD) is a major risk factor for liver cancer; therefore, its
prevention is an important clinical goal. Ablation of phosphatase and tensin homolog …

A national conference was held to better characterize the long‐term outcomes of liver
transplantation (LT) for patients with hepatocellular carcinoma (HCC) and to assess whether …

Cancer cells display altered glucose metabolism characterized by a preference for aerobic
glycolysis. The aerobic glycolytic phenotype of hepatocellular carcinoma (HCC) is often …

Liver cancer is a serious threat to public health and has fairly complicated pathogenesis.
Therefore, the identification of key genes and pathways is of much importance for clarifying …

Background & Aims Development of hepatocellular carcinoma (HCC) is associated with
alterations in the transforming growth factor-beta (TGF-β) signaling pathway, which …