Language as a biomarker for psychosis: a natural language processing approach

CM Corcoran, VA Mittal, CE Bearden, RE Gur… - Schizophrenia …, 2020 - Elsevier
Human ratings of conceptual disorganization, poverty of content, referential cohesion and
illogical thinking have been shown to predict psychosis onset in prospective clinical high risk …

EEG-based measures in at-risk mental state and early stages of schizophrenia: a systematic review

A Perrottelli, GM Giordano, F Brando, L Giuliani… - Frontiers in …, 2021 - frontiersin.org
Introduction: Electrophysiological (EEG) abnormalities in subjects with schizophrenia have
been largely reported. In the last decades, research has shifted to the identification of …

Long-term follow-up of a group at ultra high risk (“prodromal”) for psychosis: the PACE 400 study

B Nelson, HP Yuen, SJ Wood, A Lin… - JAMA …, 2013 - jamanetwork.com
Importance The ultra high-risk (UHR) criteria were introduced to prospectively identify
patients at high risk of psychotic disorder. Although the short-term outcome of UHR patients …

Neurophysiology in psychosis: The quest for disease biomarkers

B Wang, E Zartaloudi, JF Linden, E Bramon - Translational Psychiatry, 2022 - nature.com
Psychotic disorders affect 3% of the population at some stage in life, are a leading cause of
disability, and impose a great economic burden on society. Major breakthroughs in the …

Forecasting psychosis by event-related potentials—systematic review and specific meta-analysis

M Bodatsch, A Brockhaus-Dumke, J Klosterkötter… - Biological …, 2015 - Elsevier
Background Prediction and prevention of psychosis have become major research topics.
Clinical approaches warrant objective biological parameters to enhance validity in …

Electroencephalography and event-related potential biomarkers in individuals at clinical high risk for psychosis

HK Hamilton, AK Boos, DH Mathalon - Biological psychiatry, 2020 - Elsevier
Clinical outcomes vary among youths at clinical high risk for psychosis (CHR-P), with
approximately 20% progressing to full-blown psychosis over 2 to 3 years and 30% achieving …

Clinical high risk and first episode schizophrenia: auditory event-related potentials

EC Del Re, KM Spencer, N Oribe… - Psychiatry Research …, 2015 - Elsevier
The clinical high risk (CHR) period is a phase denoting a risk for overt psychosis during
which subacute symptoms often appear, and cognitive functions may deteriorate. To …

Event-related potentials in the clinical high-risk (CHR) state for psychosis: a systematic review

JR Lepock, R Mizrahi, M Korostil… - Clinical EEG and …, 2018 - journals.sagepub.com
There is emerging evidence that identification and treatment of individuals in the prodromal
or clinical high-risk (CHR) state for psychosis can reduce the probability that they will …

Targeting of α7 nicotinic acetylcholine receptors in the treatment of schizophrenia and the use of auditory sensory gating as a translational biomarker

K Hashimoto - Current pharmaceutical design, 2015 - ingentaconnect.com
Accumulating evidence suggests that the α7 subtype of nicotinic acetylcholine receptors
(nAChRs) plays a key role in inflammatory processes, thought to be involved in the …

Auditory N100 gating in patients with schizophrenia: a systematic meta-analysis

T Rosburg - Clinical Neurophysiology, 2018 - Elsevier
Objective The study sought to assess the presence of auditory N100 gating deficits in
patients with schizophrenia by meta-analysis. Methods Literature was screened for studies …