Influenza virus has resurfaced recently from inactivity during the early stages of the COVID-
19 pandemic, raising serious concerns about the nature and magnitude of future epidemics …

Seasonal influenza virus vaccines are effective when they are well matched to circulating
strains. Because of antigenic drift/change in the immunodominant hemagglutinin (HA) head …

Recombinant native-like HIV-1 envelope glycoprotein (Env) trimers are used in candidate
vaccines aimed at inducing broadly neutralizing antibodies. While state-of-the-art SOSIP or …

Influenza A virus is a highly mutable pathogenic pathogen that could cause a global
pandemic. It is necessary to find new anti-influenza drugs to resist influenza epidemics due …

Microfluidic mixing is an essential unit operation in miniaturized analytical systems.
Achieving high mixing efficiency is considerably difficult in conventional microfluidic …

Broadly neutralizing antibodies (bnAbs) targeting the hemagglutinin (HA) stem of influenza
A viruses (IAVs) tend to be effective against either group 1 or group 2 viral diversity. In rarer …

Immunogen design approaches aim to control the specificity and quality of antibody
responses elicited by next-generation vaccines. Here, we use computational protein design …

Antibodies are frontline defenders against influenza virus infection, providing protection
through multiple complementary mechanisms. Although a subset of monoclonal antibodies …

Enhancing cross-protections against diverse influenza viruses is desired for influenza
vaccinations. Neuraminidase (NA)-specific antibody responses have been found to …

Influenza virus has resurfaced recently from inactivity during the early stages of the COVID-
19 pandemic, raising serious concerns about the nature and magnitude of future epidemics …