Sodium–glucose co‐transporter 2 inhibitors as an early, first‐line therapy in patients with heart failure and reduced ejection fraction

D Tomasoni, GC Fonarow, M Adamo… - European journal of …, 2022 - Wiley Online Library
Sodium–glucose co‐transporter 2 (SGLT2) inhibitors have recently been recommended as a
foundational therapy for patients with heart failure (HF) and reduced ejection fraction …

Heart failure: an update from the last years and a look at the near future

M Riccardi, AM Sammartino, M Piepoli… - ESC heart …, 2022 - Wiley Online Library
In the last years, major progress occurred in heart failure (HF) management. Quadruple
therapy is now mandatory for all the patients with HF with reduced ejection fraction. Whilst …

Inotropic therapy in patients with advanced heart failure. A clinical consensus statement from the Heart Failure Association of the European Society of Cardiology

F Gustafsson, K Damman, S Nalbantgil… - European Journal of …, 2023 - Wiley Online Library
This clinical consensus statement reviews the use of inotropic support in patients with
advanced heart failure. The current guidelines only support use of inotropes in the setting of …

Advanced heart failure: guideline‐directed medical therapy, diuretics, inotropes, and palliative care

D Tomasoni, JKK Vishram‐Nielsen… - ESC heart …, 2022 - Wiley Online Library
Heart failure (HF) is a major cause of mortality, hospitalizations, and reduced quality of life
and a major burden for the healthcare system. The number of patients that progress to an …

A year in heart failure: an update of recent findings

L Stretti, D Zippo, AJS Coats, MS Anker… - ESC Heart …, 2021 - Wiley Online Library
Major changes have occurred in these last years in heart failure (HF) management.
Landmark trials and the 2021 European Society of Cardiology guidelines for the diagnosis …

Effects of omecamtiv mecarbil in heart failure with reduced ejection fraction according to blood pressure: the GALACTIC-HF trial

M Metra, M Pagnesi, BL Claggett, R Díaz… - European Heart …, 2022 - academic.oup.com
Aim Patients with heart failure with reduced ejection fraction and low systolic blood pressure
(SBP) have high mortality, hospitalizations, and poorly tolerate evidence-based medical …

Network meta‐analysis of medical therapy efficacy in more than 90,000 patients with heart failure and reduced ejection fraction

V De Marzo, G Savarese, L Tricarico… - Journal of internal …, 2022 - Wiley Online Library
Background Following the availability of new drugs for chronic heart failure (HF) with
reduced ejection fraction (HFrEF), we sought to provide an updated and comparative …

Contemporary drug treatment of advanced heart failure with reduced ejection fraction

JKK Vishram-Nielsen, D Tomasoni, F Gustafsson… - Drugs, 2022 - Springer
The introduction of multiple new pharmacological agents over the past three decades in the
field of heart failure with reduced ejection fraction (HFrEF) has led to reduced rates of …

Contemporary clinical role of echocardiography in patients with advanced heart failure

V Nuzzi, P Manca, M Mulè, S Leone, L Fazzini… - Heart Failure …, 2024 - Springer
Echocardiography represents an essential tool for imagers and clinical cardiologists in the
management of patients with heart failure. Advanced heart failure (AdHF) is a more severe …

Clinical impact of changes in mitral regurgitation severity after medical therapy optimization in heart failure

M Pagnesi, M Adamo, IE Sama, SD Anker… - Clinical Research in …, 2022 - Springer
Background Few data are available regarding changes in mitral regurgitation (MR) severity
with guideline-recommended medical therapy (GRMT) in heart failure (HF). Our aim was to …