Background Operative injury to the body from all procedures causes a stereotypical cascade
of neuroendocrine, cytokine, myeloid, and acute phase responses. This response has been …

Glucocorticoids are frequently used to prevent post‐operative nausea and vomiting (PONV),
and may be part of multimodal analgesic regimes. The objective of this review was to …

Controlling postoperative pain and nausea after total joint arthroplasty remains an important
challenge. We conducted a prospective, randomized controlled trial with 120 patients to …

Background Dexamethasone is a potent analgesic and antiemetic. However, the benefit of
dexamethasone after TKA is unclear, as is the efficacy in a current multimodal regime …

Background Several studies have investigated the effects of dexamethasone on post-
operative cognitive dysfunction (POCD) or post-operative delirium (POD); however, their …

Regional anaesthesia offers significant advantages in patients undergoing knee joint
arthroplasty. Novel regional anaesthetic techniques have been introduced as part of a …

Background Systemic steroid has been used to control pain and nausea in total knee
arthroplasty (TKA), but most studies recommend a single dose administration prior to, or …

Objective: To investigate the effects of intravenous administration of dexamethasone on
early postoperative cognitive dysfunction (POCD). Methods: In this prospective randomized …

Background The optimal route for dexamethasone (DEX) administration regimen for patients
undergoing primary TKA has not been investigated. This study aims to determine whether …

Current trends in orthopaedic surgery have explored different forms of adjuvant treatments to
minimize postoperative pain and the risk of nausea and vomiting. A small single …