Semen rheology and its relation to male infertility

G Tomaiuolo, F Fellico, V Preziosi… - Interface …, 2022 - royalsocietypublishing.org
Infertility affects 15% of couples of reproductive age worldwide. In spite of many advances in
understanding and treating male infertility, there is still a number of issues that need further …

The TGF-β pathway plays a key role in aortic aneurysms

T Tingting, F Wenjing, Z Qian, W Hengquan, Z Simin… - Clinica chimica acta, 2020 - Elsevier
Aortic dissection and aortic aneurysms are currently among the most high-risk
cardiovascular diseases due to their rapid onset and high mortality. Although aneurysm …

[HTML][HTML] Hypothalamic and ovarian transcriptome profiling reveals potential candidate genes in low and high egg production of white Muscovy ducks (Cairina …

SF Bello, H Xu, L Guo, K Li, M Zheng, Y Xu, S Zhang… - Poultry Science, 2021 - Elsevier
In China, the low egg production rate is a major challenge to Muscovy duck farmers.
Hypothalamus and ovary play essential role in egg production of birds. However, there are …

Melatonin abrogates the anti-developmental effect of the AKT inhibitor SH6 in bovine oocytes and embryos

M El Sheikh, A Mesalam, AA Mesalam… - International Journal of …, 2019 - mdpi.com
Melatonin, a nighttime-secreted antioxidant hormone produced by the pineal gland, and
AKT, a serine/threonine-specific protein kinase, have been identified as regulators for …

Downregulation of PI3K/AKT/mTOR pathway in Juglone-treated bovine oocytes

M El-Sheikh, A Mesalam, AAK Khalil, M Idrees, MJ Ahn… - Antioxidants, 2023 - mdpi.com
We have previously reported that juglone, a natural compound found in Juglandaceae with
a wide range of biological activities, can reduces the developmental competence of bovine …

Nobiletin enhances the development and quality of bovine embryos in vitro during two key periods of embryonic genome activation

K Cañón-Beltrán, YN Cajas, S Peréz-Cerezales… - Scientific reports, 2021 - nature.com
In vitro culture can alter the development and quality of bovine embryos. Therefore, we
aimed to evaluate whether nobiletin supplementation during EGA improves embryonic …

Differential regulation of Hippo signaling pathway components between 8‐cell and blastocyst stages of bovine preimplantation embryogenesis

J Sharma, P Madan - Molecular Reproduction and …, 2022 - Wiley Online Library
The Hippo signaling pathway is an important regulator of lineage segregation
(trophectoderm and inner cell mass) during blastocyst formation in the mouse embryos …

[HTML][HTML] Assessment of microRNA profiles in small extracellular vesicles isolated from bovine colostrum with different immunoglobulin G concentrations

T Ma, W Li, Y Chen, ER Cobo, C Windeyer… - JDS communications, 2022 - Elsevier
The consumption of bovine colostrum by newborn calves during the first days of life is
essential to ensure the transfer of passive immunity. In addition to critical IgG, colostrum also …

A Role of PI3K/Akt Signaling in Oocyte Maturation and Early Embryo Development

J Kalous, D Aleshkina, M Anger - Cells, 2023 - mdpi.com
A serine/threonine-specific protein kinase B (PKB), also known as Akt, is a key factor in the
phosphoinositide 3-kinase (PI3K)/Akt signaling pathway that regulates cell survival …

An Update on Physiopathological Roles of Akt in the ReprodAKTive Mammalian Ovary

C Giaccari, S Antonouli, G Anifandis, S Cecconi… - Life, 2024 - mdpi.com
The phosphoinositide 3-kinase (PI3K)/Akt pathway is a key signaling cascade responsible
for the regulation of cell survival, proliferation, and metabolism in the ovarian …