Paramagnetic chemical probes for studying biological macromolecules
Paramagnetic chemical probes have been used in electron paramagnetic resonance (EPR)
and nuclear magnetic resonance (NMR) spectroscopy for more than four decades. Recent …
and nuclear magnetic resonance (NMR) spectroscopy for more than four decades. Recent …
[HTML][HTML] Covalent labeling of nucleic acids
N Klöcker, FP Weissenboeck… - Chemical Society Reviews, 2020 - pubs.rsc.org
Labeling of nucleic acids is required for many studies aiming to elucidate their functions and
dynamics in vitro and in cells. Out of the numerous labeling concepts that have been …
dynamics in vitro and in cells. Out of the numerous labeling concepts that have been …
Long-range distance determinations in biomacromolecules by EPR spectroscopy
O Schiemann, TF Prisner - Quarterly reviews of biophysics, 2007 - cambridge.org
Electron paramagnetic resonance (EPR) spectroscopy provides a variety of tools to study
structures and structural changes of large biomolecules or complexes thereof. In order to …
structures and structural changes of large biomolecules or complexes thereof. In order to …
NMR approaches for structural analysis of multidomain proteins and complexes in solution
NMR spectroscopy is a key method for studying the structure and dynamics of (large)
multidomain proteins and complexes in solution. It plays a unique role in integrated …
multidomain proteins and complexes in solution. It plays a unique role in integrated …
Spin labeling EPR
JP Klare, HJ Steinhoff - Photosynthesis research, 2009 - Springer
Site-directed spin labeling in combination with electron paramagnetic resonance
spectroscopy has emerged as an efficient tool to elucidate the structure and conformational …
spectroscopy has emerged as an efficient tool to elucidate the structure and conformational …
[PDF][PDF] Long-range distance measurements on nucleic acids in cells by pulsed EPR spectroscopy
I Krstic, R Hansel, O Romainczyk, JW Engels… - Angew. Chem. Int …, 2011 - prisner.de
The tertiary structure and conformational dynamics of ribonucleic acids (RNAs) are essential
for their function as biological catalysts, regulators, and structural scaffolds.[1] X-ray …
for their function as biological catalysts, regulators, and structural scaffolds.[1] X-ray …
In‐cell EPR: progress towards structural studies inside cells
Exploring the structure and dynamics of biomolecules in the context of their intracellular
environment has become the ultimate challenge for structural biology. As the cellular …
environment has become the ultimate challenge for structural biology. As the cellular …
Paramagnetic labelling of proteins and oligonucleotides for NMR
Paramagnetic effects offer a rich source of long-range structural restraints. Here we review
current methods for site-specific tagging of proteins and oligonucleotides with paramagnetic …
current methods for site-specific tagging of proteins and oligonucleotides with paramagnetic …
Fluorescent nucleoside analogs: probes for investigating nucleic acid structure and function
AA Tanpure, MG Pawar… - Israel Journal of …, 2013 - Wiley Online Library
Base‐modified fluorescent nucleoside analog probes have been very valuable in the study
of nucleic acid structure and function. Many of them structurally resemble natural bases, and …
of nucleic acid structure and function. Many of them structurally resemble natural bases, and …
The ribosome assembly factor Nep1 responsible for Bowen–Conradi syndrome is a pseudouridine-N1-specific methyltransferase
JP Wurm, B Meyer, U Bahr, M Held… - Nucleic acids …, 2010 - academic.oup.com
ABSTRACT Nep1 (Emg1) is a highly conserved nucleolar protein with an essential function
in ribosome biogenesis. A mutation in the human Nep1 homolog causes Bowen–Conradi …
in ribosome biogenesis. A mutation in the human Nep1 homolog causes Bowen–Conradi …