Role of basic fibroblast growth factor in cancer: biological activity, targeted therapies, and prognostic value

A Ardizzone, V Bova, G Casili, A Repici, M Lanza… - Cells, 2023 - mdpi.com
Cancer is the leading cause of death worldwide; thus, it is necessary to find successful
strategies. Several growth factors, such as vascular endothelial growth factor (VEGF), basic …

A comprehensive update on the bioactive compounds from seagrasses

CMP Gono, P Ahmadi, T Hertiani, E Septiana, MY Putra… - Marine Drugs, 2022 - mdpi.com
Marine angiosperms produce a wide variety of secondary metabolites with unique structural
features that have the potential to be developed as effective and potent drugs for various …

Pull the plug: anti‐angiogenesis potential of natural products in gastrointestinal cancer therapy

Y Ai, Z Zhao, H Wang, X Zhang, W Qin… - Phytotherapy …, 2022 - Wiley Online Library
Gastrointestinal cancer (GIC), including gastric cancer and colorectal cancer, is a common
malignant tumor originating from the gastrointestinal epithelium. Although the pathogenesis …

Natural marine products: Anti-colorectal cancer in vitro and in vivo

N Han, J Li, X Li - Marine drugs, 2022 - mdpi.com
Colorectal cancer, a malignant tumor with high mortality, has a poor prognosis due to drug
resistance and toxicity in clinical surgery and chemotherapy. Thus, finding safer and more …

Stimulators of immunogenic cell death for cancer therapy: focusing on natural compounds

M Amiri, O Molavi, S Sabetkam, S Jafari… - Cancer Cell …, 2023 - Springer
A growing body of evidence indicates that the anticancer effect of the immune system can be
activated by the immunogenic modulation of dying cancer cells. Cancer cell death, as a …

Antiproliferative, antiangiogenic, and antimetastatic therapy response by mangiferin in a syngeneic immunocompetent colorectal cancer mouse model involves …

JC Rodriguez-Gonzalez… - Frontiers in …, 2021 - frontiersin.org
In spite of the current advances and achievements in cancer treatments, colorectal cancer
(CRC) persists as one of the most prevalent and deadly tumor types in both men and women …

Anticancer Drug Development: Evaluative Architecture

DY Lu, B Xu, TR Lu - Letters in Drug Design & Discovery, 2024 - ingentaconnect.com
Anticancer drug development is complex and multi-factorial, demanding robust drug
evaluative architecture in experimental and preclinical studies. To increase the number of …

[HTML][HTML] OMICS applications for medicinal plants in gastrointestinal cancers: Current advancements and future perspectives

R Dai, M Liu, X Xiang, Y Li, Z Xi, H Xu - Frontiers in Pharmacology, 2022 - frontiersin.org
Gastrointestinal cancers refer to a group of deadly malignancies of the gastrointestinal tract
and organs of the digestive system. Over the past decades, considerable amounts of …

Antioxidant Activity, Inhibition of Intestinal Cancer Cell Growth and Polyphenolic Compounds of the Seagrass Posidonia oceanica's Extracts from Living Plants and …

A Kevrekidou, AN Assimopoulou, V Trachana… - Marine Drugs, 2024 - mdpi.com
The aim of the present study was to investigate the use of Posidonia oceanica for making
products beneficial for human health. Firstly, we demonstrated that the antioxidant defense …

Using omics approaches to dissect the therapeutic effects of Chinese herbal medicines on gastrointestinal cancers

SY Li, WJ Wang, QY Li, PH Yang, XL Li… - Frontiers in …, 2022 - frontiersin.org
Chinese herbal medicines offer a rich source of anti-cancer drugs. Differences between the
pharmacology of Chinese herbal medicines and modern synthetic chemicals hinder the …