Retinal applications of swept source optical coherence tomography (OCT) and optical coherence tomography angiography (OCTA)

I Lains, JC Wang, Y Cui, R Katz, F Vingopoulos… - Progress in retinal and …, 2021 - Elsevier
The advent of optical coherence tomography (OCT) revolutionized both clinical assessment
and research of vitreoretinal conditions. Since then, extraordinary advances have been …

Identifying progression in multiple sclerosis: new perspectives

M Filippi, P Preziosa, D Langdon… - Annals of …, 2020 - Wiley Online Library
The identification of progression in multiple sclerosis is typically retrospective. Given the
profound burden of progressive multiple sclerosis, and the recent development of effective …

Optical coherence tomography in multiple sclerosis: a 3‐year prospective multicenter study

F Paul, PA Calabresi, F Barkhof… - Annals of clinical …, 2021 - Wiley Online Library
Objective To evaluate changes over 3 years in the thickness of inner retinal layers including
the peripapillary retinal nerve fiber layer (pRNFL), and combined macular ganglion cell and …

Progressive multiple sclerosis is associated with faster and specific retinal layer atrophy

ES Sotirchos, N Gonzalez Caldito… - Annals of …, 2020 - Wiley Online Library
Objective Therapeutic development in progressive multiple sclerosis (PMS) has been
hampered by a lack of reliable biomarkers to monitor neurodegeneration. Optical coherence …

Retinal correlates of neurological disorders

TE Yap, SI Balendra, MT Almonte… - … advances in chronic …, 2019 - journals.sagepub.com
Considering the retina as an extension of the brain provides a platform from which to study
diseases of the nervous system. Taking advantage of the clear optical media of the eye and …

Computer-aided diagnosis of multiple sclerosis using a support vector machine and optical coherence tomography features

C Cavaliere, E Vilades, MC Alonso-Rodríguez… - Sensors, 2019 - mdpi.com
The purpose of this paper is to evaluate the feasibility of diagnosing multiple sclerosis (MS)
using optical coherence tomography (OCT) data and a support vector machine (SVM) as an …

Assessments of vessel density and foveal avascular zone metrics in multiple sclerosis: an optical coherence tomography angiography study

H Yilmaz, A Ersoy, E Icel - Eye, 2020 - nature.com
Abstract Background/Objectives To investigate optical coherence tomography angiography
(OCT-A) findings of foveal avascular zone (FAZ) metrics and macular & peripapillary vessel …

Normative data and minimally detectable change for inner retinal layer thicknesses using a semi-automated OCT image segmentation pipeline

S Motamedi, K Gawlik, N Ayadi… - Frontiers in …, 2019 - frontiersin.org
Neurodegenerative and neuroinflammatory diseases regularly cause optic nerve and retinal
damage. Evaluating retinal changes using optical coherence tomography (OCT) in diseases …

Peripapillary vessel density as early biomarker in multiple sclerosis

G Cennamo, A Carotenuto, D Montorio… - Frontiers in …, 2020 - frontiersin.org
Background: To evaluate retinal vessel density (VD) in macular and in peripapillary regions
in patients with recent onset of multiple sclerosis, at initial demyelinating event (IDE) and in …

Asymptomatic optic nerve lesions: an underestimated cause of silent retinal atrophy in MS

JB Davion, R Lopes, É Drumez, J Labreuche… - Neurology, 2020 - AAN Enterprises
Objective To evaluate the frequency of asymptomatic optic nerve lesions and their role in the
asymptomatic retinal neuroaxonal loss observed in multiple sclerosis (MS). Methods We …