Screening for fetal aneuploidies at 11 to 13 weeks

KH Nicolaides - Prenatal diagnosis, 2011 - Wiley Online Library
Effective screening for major aneuploidies can be provided in the first trimester of
pregnancy. Screening by a combination of fetal nuchal translucency and maternal serum …

Turning the pyramid of prenatal care

KH Nicolaides - Fetal diagnosis and therapy, 2011 - karger.com
The current approach to prenatal care, which involves visits at 16, 24, 28, 30, 32, 34 and 36
weeks and then weekly until delivery, was established 80 years ago. The high concentration …

[PDF][PDF] ISUOG Practice Guidelines (updated): performance of 11–14‐week ultrasound scan

CM Bilardo, R Chaoui, JA Hyett, KO Kagan… - … in Obstetrics and …, 2023 - ora.ox.ac.uk
Performing a routine first-trimester ultrasound examination at 11+ 0 to 14+ 0 weeks'
gestation is of value for confirming viability and plurality, accurate pregnancy dating …

Increased nuchal translucency with normal karyotype

AP Souka, CS Von Kaisenberg, JA Hyett… - American journal of …, 2005 - Elsevier
Increased fetal nuchal translucency (NT) thickness between 11 and 14 weeks' gestation is a
common phenotypic expression of chromosomal abnormalities, including trisomy 21 …

Multicenter study of first‐trimester screening for trisomy 21 in 75 821 pregnancies: results and estimation of the potential impact of individual risk‐orientated two‐stage …

KH Nicolaides, K Spencer, K Avgidou… - … in Obstetrics and …, 2005 - Wiley Online Library
Objectives To evaluate the performance of first‐trimester screening for trisomy 21 by a
combination of maternal age, fetal nuchal translucency (NT) and maternal serum free β …

Screening for trisomy 21 by maternal age, fetal nuchal translucency thickness, free beta‐human chorionic gonadotropin and pregnancy‐associated plasma protein‐A

KO Kagan, D Wright, A Baker, D Sahota… - … in Obstetrics and …, 2008 - Wiley Online Library
Objectives To derive a model and examine the performance of first‐trimester combined
screening by maternal age, fetal nuchal translucency (NT) thickness and maternal serum …

Physiology of the fetal circulation

T Kiserud - Seminars in Fetal and Neonatal Medicine, 2005 - Elsevier
Our understanding of fetal circulatory physiology is based on experimental animal data, and
this continues to be an important source of new insight into developmental mechanisms. A …

Ductus venosus Doppler in screening for trisomies 21, 18 and 13 and Turner syndrome at 11–13 weeks of gestation

N Maiz, C Valencia, KO Kagan, D Wright… - … in Obstetrics and …, 2009 - Wiley Online Library
Objectives To investigate the performance of first‐trimester screening for aneuploidies by
including assessment of ductus venosus flow in the combined test of maternal age, fetal …

Increased fetal nuchal translucency at 11–14 weeks

KH Nicolaides, V Heath, S Cicero - … Diagnosis: Published in …, 2002 - Wiley Online Library
Nuchal translucency (NT) is the sonographic appearance of a subcutaneous collection of
fluid behind the fetal neck. The measurement of fetal NT thickness at the 11–14‐week scan …

Cardiac defects in chromosomally normal fetuses with abnormal ductus venosus blood flow at 10–14 weeks

A Matias, I Huggon, JC Areias… - … in Obstetrics and …, 1999 - Wiley Online Library
Objective To assess a possible relationship between ductus venosus blood flow
abnormalities and cardiac defects in chromosomally normal fetuses with increased nuchal …