Obesity and cancer: a current overview of epidemiology, pathogenesis, outcomes, and management
Simple Summary Obesity has been linked to several common cancers including breast,
colorectal, esophageal, kidney, gallbladder, uterine, pancreatic, and liver cancer. Obesity …
colorectal, esophageal, kidney, gallbladder, uterine, pancreatic, and liver cancer. Obesity …
[PDF][PDF] Renal cell carcinoma: an overview of the epidemiology, diagnosis, and treatment
S Bahadoram, M Davoodi, S Hassanzadeh… - G Ital Nefrol, 2022 - researchgate.net
Renal cell carcinoma (RCC) is the most common type of urogenital cancer. It has a mortality
rate of 30-40% and is more commonly seen in men than women. In addition to gender, other …
rate of 30-40% and is more commonly seen in men than women. In addition to gender, other …
Strengthening the reporting of observational studies in epidemiology using mendelian randomisation (STROBE-MR): explanation and elaboration
VW Skrivankova, RC Richmond, BAR Woolf… - bmj, 2021 - bmj.com
Mendelian randomisation (MR) studies allow a better understanding of the causal effects of
modifiable exposures on health outcomes, but the published evidence is often hampered by …
modifiable exposures on health outcomes, but the published evidence is often hampered by …
The trans-ancestral genomic architecture of glycemic traits
Glycemic traits are used to diagnose and monitor type 2 diabetes and cardiometabolic
health. To date, most genetic studies of glycemic traits have focused on individuals of …
health. To date, most genetic studies of glycemic traits have focused on individuals of …
Type 2 diabetes and cancer: an umbrella review of observational and mendelian randomization studies
J Pearson-Stuttard, N Papadimitriou… - … Biomarkers & Prevention, 2021 - AACR
Background: Type 2 diabetes mellitus (T2DM) has been associated with an increased risk of
developing several common cancers, but it is unclear whether this association is causal. We …
developing several common cancers, but it is unclear whether this association is causal. We …
Diabetes, obesity, and cancer—pathophysiology and clinical implications
IC Lega, LL Lipscombe - Endocrine reviews, 2020 - academic.oup.com
Obesity and diabetes have both been associated with an increased risk of cancer. In the
face of increasing obesity and diabetes rates worldwide, this is a worrying trend for cancer …
face of increasing obesity and diabetes rates worldwide, this is a worrying trend for cancer …
[HTML][HTML] Body fatness associations with cancer: evidence from recent epidemiological studies and future directions
This narrative review highlights current evidence linking greater body fatness to risk of
various cancers, with focus on evidence from recent large cohort studies and pooled …
various cancers, with focus on evidence from recent large cohort studies and pooled …
GWAS of allometric body-shape indices in UK Biobank identifies loci suggesting associations with morphogenesis, organogenesis, adrenal cell renewal and cancer
Genetic studies have examined body-shape measures adjusted for body mass index (BMI),
while allometric indices are additionally adjusted for height. We performed the first genome …
while allometric indices are additionally adjusted for height. We performed the first genome …
Estimating the magnitude of cancer overdiagnosis in Australia
PP Glasziou, MA Jones, T Pathirana… - Medical Journal of …, 2020 - Wiley Online Library
Objectives To estimate the proportion of cancer diagnoses in Australia that might reasonably
be attributed to overdiagnosis by comparing current and past lifetime risks of cancer. Design …
be attributed to overdiagnosis by comparing current and past lifetime risks of cancer. Design …
Causal role of high body mass index in multiple chronic diseases: a systematic review and meta-analysis of Mendelian randomization studies
SC Larsson, S Burgess - BMC medicine, 2021 - Springer
Background Obesity is a worldwide epidemic that has been associated with a plurality of
diseases in observational studies. The aim of this study was to summarize the evidence from …
diseases in observational studies. The aim of this study was to summarize the evidence from …