Towards a universal influenza vaccine: different approaches for one goal

GA Sautto, GA Kirchenbaum, TM Ross - Virology journal, 2018 - Springer
Influenza virus infection is an ongoing health and economic burden causing epidemics with
pandemic potential, affecting 5–30% of the global population annually, and is responsible …

Alternative methods of vaccine delivery: an overview of edible and intradermal vaccines

E Criscuolo, V Caputo, RA Diotti… - Journal of …, 2019 - Wiley Online Library
Vaccines are recognized worldwide as one of the most important tools for combating
infectious diseases. Despite the tremendous value conferred by currently available vaccines …

Nanotheranostics against COVID-19: From multivalent to immune-targeted materials

P Hassanzadeh - Journal of Controlled Release, 2020 - Elsevier
Destructive impacts of COVID-19 pandemic worldwide necessitates taking more appropriate
measures for mitigating virus spread and development of the effective theranostic agents. In …

Adding functions to biomaterial surfaces through protein incorporation

MA Wronska, IB O'Connor, MA Tilbury… - Advanced …, 2016 - Wiley Online Library
The concept of biomaterials has evolved from one of inert mechanical supports with a long‐
term, biologically inactive role in the body into complex matrices that exhibit selective cell …

Bacteriophages and their immunological applications against infectious threats

E Criscuolo, S Spadini, J Lamanna… - Journal of …, 2017 - Wiley Online Library
Bacteriophage therapy dates back almost a century, but the discovery of antibiotics led to a
rapid decline in the interests and investments within this field of research. Recently, the …

Chimeric antigen receptor (CAR)-engineered T cells redirected against hepatitis C virus (HCV) E2 glycoprotein

GA Sautto, K Wisskirchen, N Clementi, M Castelli… - Gut, 2016 - gut.bmj.com
Objective The recent availability of novel antiviral drugs has raised new hope for a more
effective treatment of hepatitis C virus (HCV) infection and its severe sequelae. However, in …

A computationally optimized broadly reactive antigen subtype–specific influenza vaccine strategy elicits unique potent broadly neutralizing antibodies against …

GA Sautto, GA Kirchenbaum, RB Abreu… - The Journal of …, 2020 - journals.aai.org
Computationally optimized broadly reactive Ags (COBRA) targeting H1 elicit a broad cross-
reactive and cross-neutralizing Ab response against multiple H1N1 viral strains. To assess B …

The role of costimulation blockade in solid organ and islet xenotransplantation

KP Samy, JR Butler, P Li, DKC Cooper… - Journal of immunology …, 2017 - Wiley Online Library
Pig‐to‐human xenotransplantation offers a potential bridge to the growing disparity between
patients with end‐stage organ failure and graft availability. Early studies attempting to …

Advances in in-silico B-cell epitope prediction

P Sun, S Guo, J Sun, L Tan, C Lu… - Current Topics in …, 2019 - ingentaconnect.com
Identification of B-cell epitopes in target antigens is one of the most crucial steps for
epitopebased vaccine development, immunodiagnostic tests, antibody production, and …

Nanobionics: From plant empowering to the infectious disease treatment

P Hassanzadeh, F Atyabi, R Dinarvand - Journal of Controlled Release, 2022 - Elsevier
Infectious diseases (ID) are serious threats against the global health and socio-economic
conditions. Vaccination usually plays a key role in disease prevention, however, insufficient …