ROS: basic concepts, sources, cellular signaling, and its implications in aging pathways

AJPO de Almeida, JCPL de Oliveira… - Oxidative medicine …, 2022 - Wiley Online Library
Reactive oxygen species (ROS) are bioproducts of cellular metabolism. There is a range of
molecules with oxidizing properties known as ROS. Despite those molecules being implied …

[HTML][HTML] Oxidative stress, insulin resistance, dyslipidemia and type 2 diabetes mellitus

S Tangvarasittichai - World journal of diabetes, 2015 - ncbi.nlm.nih.gov
Oxidative stress is increased in metabolic syndrome and type 2 diabetes mellitus (T2DM)
and this appears to underlie the development of cardiovascular disease, T2DM and diabetic …

Chemical modifications of polysaccharides and their anti-tumor activities

L Xie, M Shen, Y Hong, H Ye, L Huang, J Xie - Carbohydrate Polymers, 2020 - Elsevier
With the rising trend of incidence of cancers, effective therapies are urgently needed to
control human malignancies. However, the chemotherapy drugs currently on the market …

Copper-doped MOF-based nanocomposite for GSH depleted chemo/photothermal/chemodynamic combination therapy

L Wang, Y Xu, C Liu, W Si, W Wang, Y Zhang… - Chemical Engineering …, 2022 - Elsevier
Chemodynamic therapy (CDT) can kill cancer cells by generating toxic agents within tumors
through Fenton-/Fenton-like reaction, exhibiting high tumor specificity and low systemic …

Oxidative stress: the mitochondria-dependent and mitochondria-independent pathways of apoptosis

K Sinha, J Das, PB Pal, PC Sil - Archives of toxicology, 2013 - Springer
Oxidative stress basically defines a condition in which prooxidant–antioxidant balance in the
cell is disturbed; cellular biomolecules undergo severe oxidative damage, ultimately …

Pulmonary oxidative stress, inflammation and cancer: respirable particulate matter, fibrous dusts and ozone as major causes of lung carcinogenesis through reactive …

A Valavanidis, T Vlachogianni, K Fiotakis… - International journal of …, 2013 - mdpi.com
Reactive oxygen or nitrogen species (ROS, RNS) and oxidative stress in the respiratory
system increase the production of mediators of pulmonary inflammation and initiate or …

KRAS: feeding pancreatic cancer proliferation

KL Bryant, JD Mancias, AC Kimmelman… - Trends in biochemical …, 2014 - cell.com
Oncogenic KRAS mutation is the signature genetic event in the progression and growth of
pancreatic ductal adenocarcinoma (PDAC), an almost universally fatal disease. Although it …

Plant derived and dietary phenolic antioxidants: Anticancer properties

FMF Roleira, EJ Tavares-da-Silva, CL Varela… - Food Chemistry, 2015 - Elsevier
In this paper, a review of the literature on the phenolic compounds with anticancer activity
published between 2008 and 2012 is presented. In this overview only phenolic antioxidant …

Apoptosis and oxidative stress in neurodegenerative diseases

E Radi, P Formichi, C Battisti… - Journal of Alzheimer's …, 2014 - content.iospress.com
Neurodegenerative disorders affect almost 30 million individuals leading to disability and
death. These disorders are characterized by pathological changes in disease-specific areas …

Marine peptides: Bioactivities and applications

RCF Cheung, TB Ng, JH Wong - Marine drugs, 2015 - mdpi.com
Peptides are important bioactive natural products which are present in many marine
species. These marine peptides have high potential nutraceutical and medicinal values …