The last decade has seen a dramatic increase in the use of small‐angle scattering for the
study of biological macromolecules in solution. The drive for more complete structural …

Neurexins (NXs) and neuroligins (NLs) are transsynaptically interacting cell adhesion
proteins that play a key role in the formation, maturation, activity-dependent validation, and …

Malignancy is associated with altered expression of glycans and glycoproteins that
contribute to the cellular glycocalyx. We constructed a glycoprotein expression signature …

Research has implicated mutations in the gene for neurexin‐1 (NRXN1) in a variety of
conditions including autism, schizophrenia, and nicotine dependence. To our knowledge …

Synaptic adhesion molecules are thought to play a critical role in the formation, function and
plasticity of neuronal networks. Neuroligins (NL1–4) are a family of presumptive …

The genetics underlying autism spectrum disorder (ASD) is complex and heterogeneous,
and de novo variants are found in genes converging in functional biological processes …

A fundamental physical interaction exists across the synapse. It is mediated by synaptic
adhesion molecules, and is among the earliest and most indispensable of molecular events …

Neurexins and neuroligins provide trans-synaptic connectivity by the Ca 2+-dependent
interaction of their alternatively spliced extracellular domains. Neuroligins specify synapses …

Neuroligins, postsynaptic cell adhesion molecules that are linked to neuropsychiatric
disorders, are extensively studied, but fundamental questions about their functions remain …

Many neuropsychiatric and neurodevelopmental disorders commonly share genetic risk
factors. To date, the mechanisms driving the pathogenesis of these disorders, particularly …