Background Early life adversity is related to numerous poor health outcomes in childhood;
however, dyadic interventions that promote sensitive and responsive caregiving may protect …

Estimators of biological age hold promise for use in preventive medicine, for early detection
of chronic conditions, and for monitoring the effectiveness of interventions aimed at …

Importance Child physical and emotional abuse and neglect may affect epigenetic
signatures of accelerated aging several years after the exposure. Objective To examine the …

Importance Children with developmental delays are at a heightened risk of experiencing
mental health challenges, and this risk is exacerbated among racially minoritized children …

Early-life adversity increases the risk of health problems. Interventions supporting protective
and responsive caregiving offer a promising approach to attenuating adversity-induced …

Importance Although scientific and technological discoveries have improved the health of
the US population overall, racial and ethnic minority (American Indian and Alaska Native …

Objective To examine longitudinal associations between early life threat and deprivation on
epigenetic age acceleration at ages 9 and 15 years, and to examine associations of age …

Importance Adverse childhood experiences (ACEs), potentially traumatic experiences
occurring before the age of 18 years, are associated with epigenetic aging later in life and …

Experiences of complex trauma and adversity, especially for children, are ongoing global
crises necessitating adaptation. Bioadaptability to adversity and its health consequences …

Importance Exposure to war is associated with poor mental health outcomes. Adverse and
traumatic experiences can lead to long-lasting DNA methylation changes, potentially …