Endurance exercise is a widely accessible, low-cost intervention with a variety of benefits to
multiple organ systems. Exercise improves multiple indices of physical performance and …

Amyotrophic lateral sclerosis (ALS), the major adult-onset motor neuron disease, has been
viewed almost exclusively as a disease of upper and lower motor neurons, with muscle …

Expansion of a polyglutamine tract in the androgen receptor (AR) causes spinal and bulbar
muscular atrophy (SBMA). We previously showed that Akt-mediated phosphorylation of AR …

X-linked spinal and bulbar muscular atrophy (SBMA) is characterized by adult-onset muscle
weakness and lower motor neuron degeneration. SBMA is caused by CAG-polyglutamine …

Histological and cell‐level changes in the lumbar musculature in individuals with chronic
lumbar spine degenerative conditions are not well characterized. Although prior literature …

Spinal and bulbar muscular atrophy (SBMA) is an X-linked, adult-onset neuromuscular
condition caused by an abnormal polyglutamine (polyQ) tract expansion in androgen …

Background: Cellular remodeling in rotator cuff muscles following a massive rotator cuff tear
is poorly understood. The aim of the current study was to provide histological evidence to …

Neurodegenerative diseases (NDs) are often associated with the presence of misfolded
protein inclusions. The chaperone HSPB8 is upregulated in mice, the human brain and …

Spinal and bulbar muscular atrophy (SBMA) is an X-linked, neuromuscular
neurodegenerative disease for which there is no cure. The disease is characterized by a …

Objective Identifying simple biomarkers that can predict or track disease progression in
patients with spinal muscular atrophy (SMA) remains an unmet clinical need. To test the …