Conspectus Transition-metal-catalyzed reductive coupling of electrophiles has emerged as
a powerful tool for the construction of molecules. While major achievements have been …

Titanium is the second most abundant transition metal and is already a key player in
important industrial processes (eg polyethylene). Titanium is an attractive metal to use for …

Low-valent early transition metals are often intrinsically highly reactive as a result of their
strong propensity toward oxidation to more stable high-valent states. Harnessing these …

Deoxygenative radical C–C bond-forming reactions of alcohols are a long-standing
challenge in synthetic chemistry, and the current methods rely on multistep procedures …

A new strategy for the direct cleavage of the C (sp3)–OH bond has been developed via
activation of free alcohols with neutral diphenyl boryl radical generated from sodium …

The delivery of alkyl radicals through photocatalytic deoxygenation of primary alcohols
under mild conditions is a so far unmet challenge. In this report, we present a one-pot …

Comprehensive Summary Alcohols are among the most accessible functionalities. Catalytic
deoxygenative functionalization of alcohols is highly synthetically appealing. While …

Despite the sophistication of C–H functionalization as one of the most powerful tools in
organic synthesis, methodology for performing hydrogen-atom transfer of unactivated …

Direct coupling of unactivated alcohols remains a challenge in current synthetic chemistry.
We herein demonstrate a strategy building upon in situ halogenation/reductive coupling of …

We report a catalytic method for the direct deoxygenation of various C–O bond-containing
functional groups. Using a Ni (II) pre-catalyst and silane reducing agent, alcohols, epoxides …