Photodynamic therapy (PDT) is based on the dye-sensitized photooxidation of biological
matter in the target tissue, and utilizes light activated drugs for the treatment of a wide variety …

Because of promising clinical results obtained with photodynamic therapy, more and more
photosensitizers continue to be isolated (from natural sources), synthesized and evaluated …

Plants containing aloin A, aloe emodin, and structurally related anthraquinones have long
been used as traditional medicines and in the formulation of retail products such as …

We examined the mechanism of H 2 O 2-induced cytotoxicity and its relationship to oxidation
in human leukemia cells. The HL-60 promyelocytic leukemia cell line was sensitive to H 2 O …

Photodynamic therapy has the potential to become an effective alternate to surgery for the
treatment of cancer. In recent years, there has been a focus on identifying more effective and …

Formation of free radical intermediates in a NaOH/H2O2/Fe (III) system has been studied by
ESR spectroscopy in the presence of the spin trap 5, 5‐dimethy‐1‐pyrroline N‐oxide …

15-Deacetyl-13-glycine-substituted hypocrellin B (GDHB) is a new type of hypocrellin
derivative with an enhanced red absorption longer than 600 nm and water solubility. Visible …

The 1, 4‐diamino‐substituted anthraquinones mitoxantrone and ametantrone do not
photosensitize DNA damage following illumination with visible light. In contrast, both the 1, 5 …

The synthesis of several aminoanthraquinone derivatives (AAQs), designed to suppress the
dark toxicity and to promote more efficient cancer cell photosensitization for potential use in …

This study evaluated the effects of mitoxantrone (MX), an antitumor agent, as a sensitizer to
both photodynamic and radiation therapy in DFW human melanoma cells. Cells were …