Microfluidics for pharmaceutical nanoparticle fabrication: The truth and the myth
SI Hamdallah, R Zoqlam, P Erfle, M Blyth… - International journal of …, 2020 - Elsevier
Using micro-sized channels to manipulate fluids is the essence of microfluidics which has
wide applications from analytical chemistry to material science and cell biology research …
wide applications from analytical chemistry to material science and cell biology research …
The bioavailability of drugs—the current state of knowledge
M Stielow, A Witczyńska, N Kubryń, Ł Fijałkowski… - Molecules, 2023 - mdpi.com
Drug bioavailability is a crucial aspect of pharmacology, affecting the effectiveness of drug
therapy. Understanding how drugs are absorbed, distributed, metabolized, and eliminated in …
therapy. Understanding how drugs are absorbed, distributed, metabolized, and eliminated in …
Nanosuspension-loaded dissolving bilayer microneedles for hydrophobic drug delivery to the posterior segment of the eye
Intravitreal injections (IVT) are regarded as the gold standard for effective delivery of
hydrophobic drugs to the back of the eye. However, as a highly invasive procedure, the …
hydrophobic drugs to the back of the eye. However, as a highly invasive procedure, the …
[HTML][HTML] Metronidazole nanosuspension loaded dissolving microarray patches: An engineered composite pharmaceutical system for the treatment of skin and soft …
QK Anjani, AHB Sabri, J Domínguez-Robles… - Biomaterials …, 2022 - Elsevier
Bacteroides fragilis is one of the most common causative group of microorganisms that is
associated with skin and soft tissue infections (SSTI). Metronidazole (MTZ) is the drug of …
associated with skin and soft tissue infections (SSTI). Metronidazole (MTZ) is the drug of …
In vitro-in vivo correlation in nanocarriers: From protein corona to therapeutic implications
Understanding and establishing a link between the physicochemical characteristics of
nanoparticles (NPs) and their biological interactions poses to be a great challenge in the …
nanoparticles (NPs) and their biological interactions poses to be a great challenge in the …
A review on solubility enhancement methods for poorly water-soluble drugs
A Ainurofiq, DS Putro, DA Ramadhani… - Journal of Reports in …, 2021 - journals.lww.com
One of the most important parameters in pharmacy is drug solubility. Solubility affects the
efficacy of a drug. Drug solubility has an important role in determining the concentration of a …
efficacy of a drug. Drug solubility has an important role in determining the concentration of a …
In vitro dissolution considerations associated with nano drug delivery systems
Nano drug delivery systems (NDDS) offer promising solution for the translation of future
nanomedicines. As bioavailability and therapeutic outcomes can be improved by altering the …
nanomedicines. As bioavailability and therapeutic outcomes can be improved by altering the …
Liquid antisolvent crystallization of pharmaceutical compounds: current status and future perspectives
The present work reviews the liquid antisolvent crystallization (LASC) to prepare the
nanoparticle of pharmaceutical compounds to enhance their solubility, dissolution rate, and …
nanoparticle of pharmaceutical compounds to enhance their solubility, dissolution rate, and …
Nose-to-brain delivery of rotigotine redispersible nanosuspension: In vitro and in vivo characterization
Rotigotine (RTG) is an anti-Parkinson's drug approved by the USFDA to treat motor and non-
motor symptoms of both early and advanced stages of the disease. However, issues like …
motor symptoms of both early and advanced stages of the disease. However, issues like …
Integrated Continuous Crystallization–-Spherical Agglomeration (CCSA) Process for the Intensified Manufacturing of Atorvastatin Calcium
This study applies an innovative two-stage continuous manufacturing process for
atorvastatin calcium (ASC), focusing on the integration of process intensification through …
atorvastatin calcium (ASC), focusing on the integration of process intensification through …