Synthetic photoswitches have been known for many years, but their usefulness in biology,
pharmacology, and medicine has only recently been systematically explored. Over the past …

Light is unsurpassed in its ability to modulate biological interactions. Since their discovery,
chemists have been fascinated by photosensitive molecules capable of switching between …

Reversibly altering endogenous protein levels are persistent issues. Herein, we designed
photoswitchable azobenzene-proteolysis targeting chimeras (Azo-PROTACs) by including …

Photopharmacology addresses the challenge of drug selectivity and side effects through
creation of photoresponsive molecules activated with light with high spatiotemporal …

Chiroptical properties play a crucial role not only for molecular structures and their functions
but also for advanced applications such as molecular sensing, absolute asymmetric …

Azoheteroarene photoswitches have attracted attention due to their unique properties. We
present the stationary photochromism and ultrafast photoisomerization mechanism of …

Oxytocin (OT) and vasopressin (VP) are related neuropeptides that regulate many biological
processes. In humans, OT and VP act via four G protein-coupled receptors, OTR, V1aR …

The spatiotemporal control that light affords the polymer chemists is one of the most powerful
tools at their disposal. Photochemistry has been an integral part to the development of …

Succinate dehydrogenase (SDH) is extremely important in metabolic function and biological
processes. Modulation of SDH has been reported to be a promising therapeutic target to …

Azo dyes that combine electron‐withdrawing thiazole/benzothiazole heterocycles and
electron‐donating amino groups within the very same covalent skeleton exhibit relaxation …