Gastrointestinal stromal tumours (GISTs) are mesenchymal neoplasms that arise in the
gastrointestinal tract, usually in the stomach or the small intestine and rarely elsewhere in …

Gastrointestinal stromal tumours (GISTs) are a paradigm for the development of
personalized treatment for cancer patients. The nearly simultaneous discovery of a …

Abstract Context.—Gastrointestinal stromal tumors (GISTs) are specific, generally Kit
(CD117)-positive, mesenchymal tumors of the gastrointestinal tract encompassing a majority …

Once a poorly defined pathologic oddity, in recent years, gastrointestinal stromal tumor
(GIST) has emerged as a distinct oncogenetic entity that is now center stage in clinical trials …

Purpose The ACOSOG (American College of Surgeons Oncology Group) Z9001 (Alliance)
study, a randomized, placebo-controlled trial, demonstrated that 1 year of adjuvant imatinib …

Gastrointestinal stromal tumours are the most common mesenchymal neoplasm of the
gastrointestinal tract and are highly resistant to conventional chemotherapy and …

Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumor of the
gastrointestinal (GI) tract. Soon after GIST was recognized as a tumor driven by a KIT or …

Importance Little is known about whether the duration of adjuvant imatinib influences the
prognostic significance of KIT proto-oncogene receptor tyrosine kinase (KIT) and platelet …

Gastrointestinal stromal tumor (GIST) is the most common malignant neoplasm of
mesenchymal origin and a compelling clinical and biologic model for the rational …

Gastrointestinal stromal sarcomas (GISTs) are the most common mesenchymal tumours
originating in the digestive tract. They have a characteristic morphology, are generally …