The roles of PDGF in development and during neurogenesis in the normal and diseased nervous system

K Funa, M Sasahara - Journal of Neuroimmune Pharmacology, 2014 - Springer
The four platelet-derived growth factor (PDGF) ligands and PDGF receptors (PDGFRs), α
and β (PDGFRA, PDGFRB), are essential proteins that are expressed during embryonic and …

PDGF/PDGFR axis in the neural systems

S Sil, P Periyasamy, A Thangaraj, ET Chivero… - Molecular Aspects of …, 2018 - Elsevier
Platelet-derived growth factors (PDGFs) and their receptors (PDGFRs) are expressed in
several cell types including the brain cells such as neuronal progenitors, neurons …

Supramolecular hydrogel microspheres of platelet-derived growth factor mimetic peptide promote recovery from spinal cord injury

W Wu, S Jia, H Xu, Z Gao, Z Wang, B Lu, Y Ai, Y Liu… - ACS …, 2023 - ACS Publications
Neural stem cells (NSCs) are considered to be prospective replacements for neuronal cell
loss as a result of spinal cord injury (SCI). However, the survival and neuronal differentiation …

Specific labeling of synaptic schwann cells reveals unique cellular and molecular features

R Castro, T Taetzsch, SK Vaughan, K Godbe… - Elife, 2020 - elifesciences.org
Perisynaptic Schwann cells (PSCs) are specialized, non-myelinating, synaptic glia of the
neuromuscular junction (NMJ), that participate in synapse development, function …

[HTML][HTML] Regulation of morphine-induced synaptic alterations: role of oxidative stress, ER stress, and autophagy

Y Cai, L Yang, G Hu, X Chen, F Niu, L Yuan… - The Journal of cell …, 2016 - ncbi.nlm.nih.gov
Our findings suggest that morphine dysregulates synaptic balance in the hippocampus, a
key center for learning and memory, via a novel signaling pathway involving reactive oxygen …

Crosstalk between receptor tyrosine kinases (RTKs) and G protein-coupled receptors (GPCR) in the brain: Focus on heteroreceptor complexes and related functional …

V Di Liberto, G Mudò, N Belluardo - Neuropharmacology, 2019 - Elsevier
Neuronal events are regulated by the integration of several complex signaling networks in
which G protein-coupled receptors (GPCRs) and receptor tyrosine kinases (RTKs) are …

Neural plasticity in multiple sclerosis: the functional and molecular background

DJ Ksiazek-Winiarek, P Szpakowski… - Neural …, 2015 - Wiley Online Library
Multiple sclerosis is an autoimmune neurodegenerative disorder resulting in motor
dysfunction and cognitive decline. The inflammatory and neurodegenerative changes seen …

Neurophysiology of synaptic functioning in multiple sclerosis

MS Bassi, F Mori, F Buttari, GA Marfia… - Clinical …, 2017 - Elsevier
Multiple sclerosis (MS) is an inflammatory immune-mediate disorder of the central nervous
system (CNS), primarily affecting the myelin sheath and followed by neurodegeneration …

Cocaine-mediated induction of platelet-derived growth factor: implication for increased vascular permeability

H Yao, M Duan, S Buch - Blood, The Journal of the American …, 2011 - ashpublications.org
Neuroinflammation associated with advanced HIV-1 infection is often exacerbated in
cocaine-abusing, HIV-infected patients. The underlying mechanisms could, in part, be …

Synaptic plasticity and PDGF signaling defects underlie clinical progression in multiple sclerosis

F Mori, S Rossi, S Piccinin, C Motta… - Journal of …, 2013 - Soc Neuroscience
Neuroplasticity is essential to prevent clinical worsening despite continuing neuronal loss in
several brain diseases, including multiple sclerosis (MS). The precise nature of the …