Mechanisms to mitigate the trade-off between growth and defense

TL Karasov, E Chae, JJ Herman, J Bergelson - The Plant Cell, 2017 - academic.oup.com
Plants have evolved an array of defenses against pathogens. However, mounting a defense
response frequently comes with the cost of a reduction in growth and reproduction, carrying …

Effector-triggered immunity: from pathogen perception to robust defense

H Cui, K Tsuda, JE Parker - Annual review of plant biology, 2015 - annualreviews.org
In plant innate immunity, individual cells have the capacity to sense and respond to
pathogen attack. Intracellular recognition mechanisms have evolved to intercept …

Direct pathogen-induced assembly of an NLR immune receptor complex to form a holoenzyme

S Ma, D Lapin, LI Liu, Y Sun, W Song, X Zhang… - Science, 2020 - science.org
INTRODUCTION Discrimination of self from nonself is pivotal for cellular organisms, as it
allows the perception of pathogenic invaders that might otherwise multiply unchecked and …

[HTML][HTML] Pathogen effector recognition-dependent association of NRG1 with EDS1 and SAG101 in TNL receptor immunity

X Sun, D Lapin, JM Feehan, SC Stolze… - Nature …, 2021 - nature.com
Plants utilise intracellular nucleotide-binding, leucine-rich repeat (NLR) immune receptors to
detect pathogen effectors and activate local and systemic defence. NRG1 and ADR1 …

[HTML][HTML] A plant immune receptor detects pathogen effectors that target WRKY transcription factors

PF Sarris, Z Duxbury, SU Huh, Y Ma, C Segonzac… - Cell, 2015 - cell.com
Defense against pathogens in multicellular eukaryotes depends on intracellular immune
receptors, yet surveillance by these receptors is poorly understood. Several plant nucleotide …

Diverse NLR immune receptors activate defence via the RPW 8‐NLR NRG 1

B Castel, PM Ngou, V Cevik, A Redkar, DS Kim… - New …, 2019 - Wiley Online Library
Most land plant genomes carry genes that encode RPW 8‐NLR Resistance (R) proteins.
Angiosperms carry two RPW 8‐NLR subclasses: ADR 1 and NRG 1. ADR 1s act as …

[HTML][HTML] Structure, biochemical function, and signaling mechanism of plant NLRs

J Wang, W Song, J Chai - Molecular Plant, 2023 - cell.com
To counter pathogen invasion, plants have evolved a large number of immune receptors,
including membrane-resident pattern recognition receptors (PRRs) and intracellular …

[HTML][HTML] A receptor pair with an integrated decoy converts pathogen disabling of transcription factors to immunity

C Le Roux, G Huet, A Jauneau, L Camborde… - Cell, 2015 - cell.com
Microbial pathogens infect host cells by delivering virulence factors (effectors) that interfere
with defenses. In plants, intracellular nucleotide-binding/leucine-rich repeat receptors …

A coevolved EDS1-SAG101-NRG1 module mediates cell death signaling by TIR-domain immune receptors

D Lapin, V Kovacova, X Sun, JA Dongus… - The Plant …, 2019 - academic.oup.com
Plant nucleotide binding/leucine-rich repeat (NLR) immune receptors are activated by
pathogen effectors to trigger host defenses and cell death. Toll-interleukin 1 receptor domain …

Behind the lines–actions of bacterial type III effector proteins in plant cells

D Büttner - FEMS microbiology reviews, 2016 - academic.oup.com
Pathogenicity of most Gram-negative plant-pathogenic bacteria depends on the type III
secretion (T3S) system, which translocates bacterial effector proteins into plant cells. Type III …