Advances in nanomaterials for photodynamic therapy applications: Status and challenges

J Chen, T Fan, Z Xie, Q Zeng, P Xue, T Zheng, Y Chen… - Biomaterials, 2020 - Elsevier
Photodynamic therapy (PDT), as a non-invasive therapeutic modality that is alternative to
radiotherapy and chemotherapy, is extensively investigated for cancer treatments. Although …

Nanoparticles in photodynamic therapy

SS Lucky, KC Soo, Y Zhang - Chemical reviews, 2015 - ACS Publications
Cancer accounted for 7.6 million deaths (around 13% of all deaths) worldwide in 2008.(1)
Almost 13 million cancer cases are newly diagnosed every year, and deaths are projected to …

Squaraine dyes: molecular design for different applications and remaining challenges

K Ilina, WM MacCuaig, M Laramie… - Bioconjugate …, 2019 - ACS Publications
Squaraine dyes are a class of organic dyes with strong and narrow absorption bands in the
near-infrared. Despite high molar absorptivities and fluorescence quantum yields, these …

[图书][B] CRC Handbook of Organic Photochemistry and Photobiology, Volumes 1 & 2

WM Horspool, F Lenci - 2003 - taylorfrancis.com
The second edition of this best-selling handbook is bigger, more comprehensive, and now
completely current. In addition to thorough updates to the discussions featured in the first …

NIR‐II Ratiometric Chemiluminescent/Fluorescent Reporters for Real‐Time Monitoring and Evaluating Cancer Photodynamic Therapy Efficacy

L Su, Y Chen, H Huo, N Liao, Y Wu, X Ge, Z Guo… - Small, 2022 - Wiley Online Library
The development of probes for early monitoring tumor therapy response may greatly benefit
the promotion of photodynamic therapy (PDT) efficacy. Singlet oxygen (1O2) generation is a …

[HTML][HTML] A pH-activatable and aniline-substituted photosensitizer for near-infrared cancer theranostics

J Tian, J Zhou, Z Shen, L Ding, JS Yu, H Ju - Chemical Science, 2015 - pubs.rsc.org
This work reports a newly designed pH-activatable and aniline-substituted aza-boron-
dipyrromethene as a trifunctional photosensitizer to achieve highly selective tumor imaging …

The role of photodynamic therapy (PDT) physics

TC Zhu, JC Finlay - Medical physics, 2008 - Wiley Online Library
Photodynamic therapy (PDT) is an emerging treatment modality that employs the
photochemical interaction of three components: light, photosensitizer, and oxygen …

Fluence rate as a modulator of PDT mechanisms

BW Henderson, TM Busch… - Lasers in Surgery and …, 2006 - Wiley Online Library
Abstract Background and Objectives Molecular oxygen in the tissue to be treated by
photodynamic therapy (PDT) is critical for photodynamic cell killing. The fluence rate of PDT …

[HTML][HTML] Determination of the distribution of light, optical properties, drug concentration, and tissue oxygenation in-vivo in human prostate during motexafin lutetium …

TC Zhu, JC Finlay, SM Hahn - Journal of Photochemistry and Photobiology …, 2005 - Elsevier
It is desirable to quantify the distribution of the light fluence rate, the optical properties, the
drug concentration, and the tissue oxygenation for photodynamic therapy (PDT) of prostate …

Explicit dosimetry for photodynamic therapy: macroscopic singlet oxygen modeling

KKH Wang, JC Finlay, TM Busch… - Journal of …, 2010 - Wiley Online Library
Abstract Singlet oxygen (1O2) is the major cytotoxic agent responsible for cell killing for type‐
II photodynamic therapy (PDT). An empirical four‐parameter macroscopic model is …