The involvement of the JAK-STAT signaling pathway in chronic inflammatory skin disease atopic dermatitis

L Bao, H Zhang, LS Chan - Jak-Stat, 2013 - Taylor & Francis
Atopic dermatitis (AD), a common chronic inflammatory skin disease, is characterized by
inflammatory cell skin infiltration. The JAK-STAT pathway has been shown to play an …

Interleukin‐13 in asthma pathogenesis

M Wills‐Karp - Immunological reviews, 2004 - Wiley Online Library
Bronchial asthma is a complex disorder that is thought to arise as a result of aberrant T‐
lymphocyte responses to noninfectious environmental antigens. In particular, the symptoms …

Immune regulation by histamine

M Jutel, T Watanabe, M Akdis, K Blaser… - Current opinion in …, 2002 - Elsevier
Histamine is a potent bioamine with multiple activities in various pathological and
physiological conditions. In addition to its well-characterised effects in the acute …

Trends in histamine research: new functions during immune responses and hematopoiesis

E Schneider, M Rolli-Derkinderen, M Arock… - TRENDS in Immunology, 2002 - cell.com
Histamine is a bioamine with multiple physiological activities. In the immune system, it not
only mediates the deleterious effects accompanying allergic reactions, but it acts also in a …

Interleukin-13 in asthma

M Wills-Karp, M Chiaramonte - Current opinion in pulmonary …, 2003 - journals.lww.com
Some time ago, the Th2 cytokine, interleukin (IL)-13, was identified as a critical regulator of
the allergic response. Initial studies in animal models of disease provided compelling …

Effects of histamine on Th1/Th2 cytokine balance

KA Packard, MM Khan - International immunopharmacology, 2003 - Elsevier
Atopic asthma is a chronic inflammatory disorder of the airways where upon exposure to
allergens, the body mounts an immune response. This disease is associated with an …

The H1 histamine receptor regulates allergic lung responses

PJ Bryce, CB Mathias, KL Harrison… - The Journal of …, 2006 - Am Soc Clin Investig
Histamine, signaling via the type 1 receptor (H1R), has been shown to suppress Th2
cytokine production by in vitro cultured T cells. We examined the role of H1R in allergic …

Histamine, histamine receptors, and their role in immunomodulation: an updated systematic review

M Shahid, T Tripathi, F Sobia, S Moin… - The Open …, 2009 - benthamopen.com
Histamine, a biological amine, is considered as a principle mediator of many pathological
processes regulating several essential events in allergies and autoimmune diseases. It …

Calcitonin gene-related peptide biases Langerhans cells toward Th2-type immunity

W Ding, LL Stohl, JA Wagner… - The Journal of …, 2008 - journals.aai.org
Langerhans cells (LC) are epidermal dendritic cells capable, in several experimental
systems, of Ag-presentation for stimulation of cell-mediated immunity. LC have been …

Fe-bLf nanoformulation targets survivin to kill colon cancer stem cells and maintains absorption of iron, calcium and zinc

JR Kanwar, G Mahidhara, K Roy, S Sasidharan… - …, 2015 - Taylor & Francis
Aim: To validate the anticancer efficacy of alginate-enclosed, chitosan-conjugated, calcium
phosphate, iron-saturated bovine lactoferrin (Fe-bLf) nanocarriers/nanocapsules (NCs) with …