Agriculture waste valorisation as a source of antioxidant phenolic compounds within a circular and sustainable bioeconomy

C Jimenez-Lopez, M Fraga-Corral, M Carpena… - Food & function, 2020 - pubs.rsc.org
Planet globalization, population growth and its consequent need to produce large amounts
of food, or individual economic benefits and the prioritization of this over environment health …

Inflammation, NF-κB, and chronic diseases: how are they linked?

AB Kunnumakkara, B Shabnam, S Girisa… - Critical Reviews™ in …, 2020 - dl.begellhouse.com
Most chronic diseases, caused by lifestyle factors, appear to be linked to inflammation.
Inflammation is activated mechanistically, and nuclear factor-κB (NF-κB) is a significant …

[HTML][HTML] Microbial metabolite restricts 5-fluorouracil-resistant colonic tumor progression by sensitizing drug transporters via regulation of FOXO3-FOXM1 axis

S Ghosh, R Singh, ZM Vanwinkle, H Guo… - Theranostics, 2022 - ncbi.nlm.nih.gov
The survival rate of colorectal cancer patients is adversely affected by the selection of tumors
resistant to conventional anti-cancer drugs such as 5-fluorouracil (5FU). Although there is …

Computational analysis of eugenol inhibitory activity in lipoxygenase and cyclooxygenase pathways

F Das Chagas Pereira de Andrade, AN Mendes - Scientific reports, 2020 - nature.com
Chronic inflammation is triggered by numerous diseases such as osteoarthritis, Crohn's
disease and cancer. The control of the pro-inflammatory process can prevent, mitigate …

Red beetroot and betalains as cancer chemopreventative agents

JF Lechner, GD Stoner - Molecules, 2019 - mdpi.com
Carcinogenesis is the process whereby a normal cell is transformed into a neoplastic cell.
This action involves several steps starting with initiation and followed by promotion and …

MAPK signalling pathway in cancers: Olive products as cancer preventive and therapeutic agents

I Peluso, NS Yarla, R Ambra, G Pastore… - Seminars in cancer …, 2019 - Elsevier
The mitogen-activated protein kinases (MAPKs) are fundamental in inflammation and cancer
control, through the crosstalk between the redox regulated nuclear factor E2-related factor 2 …

Chemopreventive activity of sulforaphane

X Jiang, Y Liu, L Ma, R Ji, Y Qu, Y Xin… - … design, development and …, 2018 - Taylor & Francis
Cancer is one of the major causes of morbidity and mortality in the world. Carcinogenesis is
a multistep process induced by genetic and epigenetic changes that disrupt pathways …

Antiangiogenic effect of flavonoids and chalcones: An update

L Mirossay, L Varinská, J Mojžiš - International journal of molecular …, 2017 - mdpi.com
Chalcones are precursors of flavonoid biosynthesis in plants. Both flavonoids and chalcones
are intensively investigated because of a large spectrum of their biological activities. Among …

Phytochemicals in prostate cancer: from bioactive molecules to upcoming therapeutic agents

B Salehi, PVT Fokou, LRT Yamthe, BT Tali… - Nutrients, 2019 - mdpi.com
Prostate cancer is a heterogeneous disease, the second deadliest malignancy in men and
the most commonly diagnosed cancer among men. Traditional plants have been applied to …

Viburnum opulus Fruit Phenolic Compounds as Cytoprotective Agents Able to Decrease Free Fatty Acids and Glucose Uptake by Caco-2 Cells

M Zakłos-Szyda, N Pawlik, D Polka, A Nowak… - Antioxidants, 2019 - mdpi.com
In recent years, there has been increasing interest in studying food-originated
phytocompounds with beneficial influences for humans. Amongst the most active natural …