Viral deubiquitinating proteases and the promising strategies of their inhibition

[HTML] mdpi.com

[HTML][HTML] Mechanistic Insights into Targeting SARS-CoV-2 Papain-like Protease in the Evolution and Management of COVID-19

NN Magwaza, AGA Mushebenge, SC Ugbaja… - BioChem, 2024 - mdpi.com
The COVID-19 pandemic, instigated by the emergence of the novel coronavirus, SARS-CoV-
2, created an incomparable global health crisis. Due to its highly virulent nature, identifying …
被引用次数：2 相关文章 所有 2 个版本
[PDF] cell.com

Structural diversity of the CE-clan proteases in bacteria to disarm host ubiquitin defenses

L Sánchez-Alba, H Borràs-Gas, G Huang… - Trends in Biochemical …, 2024 - cell.com
Ubiquitin (Ub) and ubiquitin-like (UbL) modifications are critical regulators of multiple
cellular processes in eukaryotes. These modifications are dynamically controlled by …
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E3 ubiquitin ligases and deubiquitinases in colorectal cancer: Emerging molecular insights and therapeutic opportunities

S Kumar, M Basu, MK Ghosh - … et Biophysica Acta (BBA)-Molecular Cell …, 2024 - Elsevier
Colorectal cancer (CRC) presents ongoing challenges due to limited treatment effectiveness
and a discouraging prognosis, underscoring the need for ground-breaking therapeutic …
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[PDF] universiteitleiden.nl

[PDF][PDF] an.(2024, No ember 19)

M Huizen - from https://hdl. handle. net/1887/4109217 … - scholarlypublications …
The coronavirus papain-like protease (PLpro) is crucial for viral replicase polyprotein
processing. Additionally, PLpro can subvert host defense mechanisms by its …
相关文章 所有 2 个版本