Oral manifestations of human papillomavirus infections

S Syrjänen - European journal of oral sciences, 2018 - Wiley Online Library
Papillomaviruses are one of the oldest viruses known, dating back 330 million years. During
this long evolution, human papillomaviruses (HPV) have developed into hijackers of human …

HPV, hypoxia and radiation response in head and neck cancer

EL Göttgens, C Ostheimer, PN Span… - The British journal of …, 2018 - academic.oup.com
Over the last decades, the incidence of human papilloma virus (HPV) positive head and
neck squamous-cell carcinoma (HNSCC) has significantly increased. Infection with high-risk …

Defining HPV-specific B cell responses in patients with head and neck cancer

A Wieland, MR Patel, MA Cardenas, CS Eberhardt… - Nature, 2021 - nature.com
Tumours often contain B cells and plasma cells but the antigen specificity of these
intratumoral B cells is not well understood,,,,,,–. Here we show that human papillomavirus …

Novel antigenic targets of HPV therapeutic vaccines

DR Boilesen, KN Nielsen, PJ Holst - Vaccines, 2021 - mdpi.com
Human papillomavirus (HPV) infection is the cause of the majority of cervical cancers and
head and neck cancers worldwide. Although prophylactic vaccines and cervical cancer …

The tumor-specific immune landscape in HPV+ head and neck cancer

JP Conarty, A Wieland - Viruses, 2023 - mdpi.com
Human papillomaviruses (HPVs) are the causative agent of several anogenital cancers as
well as head and neck cancers, with HPV+ head and neck squamous cell carcinoma …

B cells in head and neck squamous cell carcinoma: current opinion and novel therapy

X Guo, L Xu, L Nie, C Zhang, Y Liu, R Zhao… - Cancer Cell …, 2024 - Springer
Head and neck squamous cell carcinoma (HNSCC) is a common malignant tumour. Despite
advancements in surgery, radiotherapy and chemotherapy, which have improved the …

Human papillomavirus 16 E 6 antibodies are sensitive for human papillomavirus–driven oropharyngeal cancer and are associated with recurrence

KA Lang Kuhs, AR Kreimer, S Trivedi, D Holzinger… - Cancer, 2017 - Wiley Online Library
BACKGROUND Human papillomavirus 16 (HPV16) E6 antibodies may be an early marker
of the diagnosis and recurrence of human papillomavirus–driven oropharyngeal cancer …

Sensitivity and specificity of human papillomavirus (HPV) 16 early antigen serology for HPV-driven oropharyngeal cancer: a systematic literature review and meta …

J Hibbert, G Halec, D Baaken, T Waterboer, N Brenner - Cancers, 2021 - mdpi.com
Simple Summary Serum antibodies against human papillomavirus 16 (HPV16) proteins are
associated with HPV-driven oropharyngeal cancer (HPV-OPC). The HPV status of OPC …

The role of HPV in determining treatment, survival, and prognosis of head and neck squamous cell carcinoma

I Sharkey Ochoa, E O'Regan, M Toner, E Kay, P Faul… - Cancers, 2022 - mdpi.com
Simple Summary Head and neck squamous cell carcinoma (HNSCC) incidence has been
escalating in the last two decades, particularly in Western Europe and North America …

Evolution of a paradigm switch in diagnosis and treatment of HPV-driven head and neck cancer—striking the balance between toxicity and cure

B Tawk, J Debus, A Abdollahi - Frontiers in Pharmacology, 2022 - frontiersin.org
More than a decade after the discovery of p16 immunohistochemistry (IHC) as a surrogate
for human papilloma virus (HPV)-driven head and neck squamous cell carcinoma (HNSCC) …