Tenosynovial giant cell tumor (TGCT) is a rare and locally aggressive benign tumor arising
from the synovium of joints, bursae, and tendon sheaths. It is classified into localized (L …

Tumor-associated macrophages (TAMs) are one of the most plentiful immune compositions
in the tumor microenvironment, which are further divided into anti-tumor M1 subtype and pro …

Background Sepsis-associated encephalopathy (SAE) is characterized by symptoms of
delirium including hallucinations, impaired concentration, agitation, or coma and is …

Abstract Background and Objectives Surgery is the mainstay of treatment for tenosynovial
giant cell tumors (TGCTs). However, achieving a cure through surgery alone remains …

Microglia are innate immune cells in the brain and show exceptional heterogeneity. They
are key players in brain physiological development regulating synaptic plasticity and …

Pigmented villonodular synovitis is a benign soft-tissue lesion that can affect the synovium of
joint spaces, bursae, or tendon sheaths. It is a rare condition and even rarer when it …

Background Diffuse-type tenosynovial giant cell tumor (D-TGCT) is a mono-articular, soft-
tissue tumor. Although it can behave locally aggressively, D-TGCT is a non-malignant …

Tenosynovial giant cell tumors (TSGCTs) are rare tumors arising in tendons or the synoviae
of joints and bursae. The localized type is benign while the diffuse type shows expansive …

After a decade of approval of the drug vemurafenib in 2011, the hopeless scenario imposed
by some severe cancer types has been mitigated by the magic bullets developed through …

Background: Tenosynovial giant cell tumor (TGCT) is a monoarticular fibrohistiocytic benign
or locally aggressive soft tissue tumor that originates from the synovium of joints, bursae …