Nitric oxide: physiological functions, delivery, and biomedical applications
Nitric oxide (NO) is a gaseous molecule that has a central role in signaling pathways
involved in numerous physiological processes (eg, vasodilation, neurotransmission …
involved in numerous physiological processes (eg, vasodilation, neurotransmission …
Nitric oxide signalling in cardiovascular health and disease
C Farah, LYM Michel, JL Balligand - Nature Reviews Cardiology, 2018 - nature.com
Nitric oxide (NO) signalling has pleiotropic roles in biology and a crucial function in
cardiovascular homeostasis. Tremendous knowledge has been accumulated on the …
cardiovascular homeostasis. Tremendous knowledge has been accumulated on the …
[HTML][HTML] Mitochondrial ROS-induced ROS release: an update and review
DB Zorov, M Juhaszova, SJ Sollott - Biochimica et Biophysica Acta (BBA) …, 2006 - Elsevier
Unstable mitochondrial membrane potential and redox transitions can occur following
insults including ischemia/reperfusion injury and toxin exposure, with negative …
insults including ischemia/reperfusion injury and toxin exposure, with negative …
Glycogen synthase kinase-3β mediates convergence of protection signaling to inhibit the mitochondrial permeability transition pore
M Juhaszova, DB Zorov, SH Kim… - The Journal of …, 2004 - Am Soc Clin Investig
Environmental stresses converge on the mitochondria that can trigger or inhibit cell death.
Excitable, postmitotic cells, in response to sublethal noxious stress, engage mechanisms …
Excitable, postmitotic cells, in response to sublethal noxious stress, engage mechanisms …
Cardiac endothelial-myocardial signaling: its role in cardiac growth, contractile performance, and rhythmicity
DL Brutsaert - Physiological reviews, 2003 - journals.physiology.org
Experimental work during the past 15 years has demonstrated that endothelial cells in the
heart play an obligatory role in regulating and maintaining cardiac function, in particular, at …
heart play an obligatory role in regulating and maintaining cardiac function, in particular, at …
Cardiac mechano-electric coupling: acute effects of mechanical stimulation on heart rate and rhythm
The heart is vital for biological function in almost all chordates, including humans. It beats
continually throughout our life, supplying the body with oxygen and nutrients while removing …
continually throughout our life, supplying the body with oxygen and nutrients while removing …
Calcium sparks
H Cheng, WJ Lederer - Physiological reviews, 2008 - journals.physiology.org
The calcium ion (Ca2+) is the simplest and most versatile intracellular messenger known.
The discovery of Ca2+ sparks and a related family of elementary Ca2+ signaling events has …
The discovery of Ca2+ sparks and a related family of elementary Ca2+ signaling events has …
eNOS activation by physical forces: from short-term regulation of contraction to chronic remodeling of cardiovascular tissues
Nitric oxide production in response to flow-dependent shear forces applied on the surface of
endothelial cells is a fundamental mechanism of regulation of vascular tone, peripheral …
endothelial cells is a fundamental mechanism of regulation of vascular tone, peripheral …
Mutation in human desmoplakin domain binding to plakoglobin causes a dominant form of arrhythmogenic right ventricular cardiomyopathy
A Rampazzo, A Nava, S Malacrida, G Beffagna… - The American Journal of …, 2002 - cell.com
Arrhythmogenic right ventricular cardiomyopathy (ARVD/C) is a genetically heterogeneous
disease characterized by progressive degeneration of the right ventricular myocardium and …
disease characterized by progressive degeneration of the right ventricular myocardium and …
Nitric oxide and cardiac function: ten years after, and continuing
Nitric oxide (NO) is produced from virtually all cell types composing the myocardium and
regulates cardiac function through both vascular-dependent and-independent effects. The …
regulates cardiac function through both vascular-dependent and-independent effects. The …