Mitochondria are extremely active organelles that perform a variety of roles in the cell
including energy production, regulation of calcium homeostasis, apoptosis, and population …

Neurodegenerative diseases are adult-onset neurological conditions that are notoriously
difficult to model for drug discovery and development because most models are unable to …

The cytokine-activated Janus kinase (JAK)–signal transducer and activator of transcription
(STAT) cascade is a pleiotropic pathway that involves receptor subunit multimerization. The …

Objectives: Alzheimer's disease (AD) is one of the most common forms of
neurodegenerative diseases. Despite vast ongoing researches focusing on the area, little is …

Neurodegenerative disorders (NDD) have grabbed significant scientific consideration due to
their fast increase in prevalence worldwide. The specific pathophysiology of the disease and …

Alzheimer's disease (AD) is a neurodegenerative disorder that causes progressive loss of
cognitive functions like thinking, memory, reasoning, behavioral abilities, and social skills …

Currently, all the existing treatments for Alzheimer's disease (AD) fail to stall progression due
to longer duration of time between onset of the symptoms and diagnosis of the disease …

Alzheimer's disease (AD) is an irreversible and neurodegenerative disorder. Its etiology is
not clear, but the involvement of genetic components plays a central role in the onset of the …

In Alzheimer's disease (AD), molecular changes are observed not only in patients' neurons
but also in peripheral cells, such as blood lymphocytes. These include changes in the level …

Alzheimer's disease is a common neurodegenerative disease in the elderly population and
a leading cause of dementia. Genetics and environmental risk factors were considered to …