Cyclic decidualization of the human endometrium in reproductive health and failure

B Gellersen, JJ Brosens - Endocrine reviews, 2014 - academic.oup.com
Decidualization denotes the transformation of endometrial stromal fibroblasts into
specialized secretory decidual cells that provide a nutritive and immunoprivileged matrix …

Human placental trophoblast invasion and differentiation: a particular focus on Wnt signaling

M Knöfler, J Pollheimer - Frontiers in genetics, 2013 - frontiersin.org
Wingless ligands, a family of secreted proteins, are critically involved in organ development
and tissue homeostasis by ensuring balanced rates of stem cell proliferation, cell death and …

Genetic associations with gestational duration and spontaneous preterm birth

G Zhang, B Feenstra, J Bacelis, X Liu… - … England Journal of …, 2017 - Mass Medical Soc
Background Despite evidence that genetic factors contribute to the duration of gestation and
the risk of preterm birth, robust associations with genetic variants have not been identified …

[HTML][HTML] Understanding the impact of uterine fibroids on human endometrium function

A Navarro, MV Bariani, Q Yang… - Frontiers in cell and …, 2021 - frontiersin.org
Uterine fibroids (leiomyomas) are the most common benign gynecological tumors in women
of reproductive age worldwide. They cause heavy menstrual bleeding, usually leading to …

Progesterone‐regulated endometrial factors controlling implantation

AS Bhurke, IC Bagchi, MK Bagchi - American journal of …, 2016 - Wiley Online Library
The steroid hormone progesterone (P), acting via the progesterone receptor (PR) isoforms,
PR‐A and PR‐B, exerts a profound influence on uterine functions during early gestation. In …

Near-infrared light-triggered porous AuPd alloy nanoparticles to produce mild localized heat to accelerate bone regeneration

X Zhang, G Cheng, X Xing, J Liu, Y Cheng… - The journal of …, 2019 - ACS Publications
The treatment of massive bone defects is still a significant challenge for orthopedists. Here
we have engineered synthetic porous AuPd alloy nanoparticles (pAuPds) as a hyperthermia …

Roles and action mechanisms of WNT4 in cell differentiation and human diseases: a review

Q Zhang, Y Pan, J Ji, Y Xu, Q Zhang, L Qin - Cell death discovery, 2021 - nature.com
Abstract WNT family member 4 (WNT4), which belongs to the conserved WNT protein family,
plays an important role in the development and differentiation of many cell types during the …

Implantation and establishment of pregnancy in human and nonhuman primates

RW Su, AT Fazleabas - Regulation of Implantation and Establishment of …, 2015 - Springer
Implantation and the establishment of pregnancy are critical for the propagation of the
species, but yet remain the limiting steps in human and primate reproduction. Successful …

Decreased Notch pathway signaling in the endometrium of women with endometriosis impairs decidualization

RW Su, MR Strug, NR Joshi, JW Jeong… - The Journal of …, 2015 - academic.oup.com
Context: Endometriosis is a common gynecological disease affecting one in 10 women of
reproductive age and is a major cause of pelvic pain and impaired fertility. Endometrial …

90 years of progesterone: new insights into progesterone receptor signaling in the endometrium required for embryo implantation

FJ DeMayo, JP Lydon - Journal of Molecular Endocrinology, 2020 - jme.bioscientifica.com
Progesterone's ability to maintain pregnancy in eutherian mammals highlighted this steroid
as the “hormone of pregnancy”. It was the unique “pro-gestational” bioactivity of …