Angiogenesis and lymphangiogenesis often occur in response to tissue injury or in the
presence of pathology (eg, cancer), and it is these types of environments in which …

Because virtually all tissues contain blood vessels, the importance of hemevascularization
has been long recognized in regenerative medicine and tissue engineering. However, the …

Dysfunction of the lymphatic system is associated with a wide range of disease phenotypes.
The restoration of dysfunctional lymphatic vessels has been hypothesized as an innovative …

Tumor‑associated macrophages (TAMs) are crucial cells of the tumor microenvironment
(TME), which belong to the innate immune system and regulate primary tumor growth …

Triple negative breast cancer (TNBC) is a significant clinical problem to which
immunotherapeutic strategies have been applied with limited success. Using the syngeneic …

The lymphatic system plays a significant role in homeostasis and drainage of excess fluid
back into venous circulation. Lymphatics are also associated with a number of diseases …

The lymphatic vasculature is an essential component of the body's circulation providing a
network of vessels to return fluid and proteins from the tissue space to the blood, to facilitate …

Recent studies have demonstrated that chronic inflammation-induced lymphangiogenesis
plays a crucial role in the progression of various renal diseases, including diabetic …

Myocardial infarction, caused by a thrombus or coronary vascular occlusion, leads to
irreversible ischaemic injury. Advances in early reperfusion strategies have significantly …

Colorectal cancer (CRC) is one of the leading causes of cancer mortality. Angiogenesis is a
rate-determining step in CRC development and metastasis. The balance of angiogenic and …