Introduction Irreversible electroporation (IRE) is a relatively new ablation method for the
treatment of unresectable cancers. Although the main mechanism of IRE is electric …

BACKGROUND In the first studies of electrochemotherapy (ECT), small cutaneous
metastases were treated and only mild or moderate pain was observed; therefore, pain was …

High-frequency irreversible electroporation (H-FIRE) has emerged as an alternative to
conventional irreversible electroporation (IRE) to overcome the issues associated with …

For irreversible-electroporation (IRE)-based therapies, the underlying electric field
distribution in the target tissue is influenced by the electroporation-induced conductivity …

This paper describes the operation of a solid-state generator proposed to produce high-
frequency bipolar high-voltage pulse bursts on resistive-type loads, intended for medical …

Irreversible electroporation, as a nonthermal therapy of prostate cancer, has been used in
clinic for several years. The mechanism of irreversible electroporation ablation is thermal …

Purpose To compare the intensity of muscle contractions in irreversible electroporation (IRE)
treatments when traditional IRE and high-frequency IRE (H-FIRE) waveforms are used in …

It was recently suggested that applying high-frequency short biphasic pulses (HF-IRE)
reduces pain and muscle contractions in electrochemotherapy and irreversible ablation …

High-frequency irreversible electroporation (H-FIRE) is a tissue ablation modality employing
bursts of electrical pulses in a positive phase–interphase delay (d 1)–negative phase …

To achieve high efficiency of electroporation and to minimize unwanted side effects, the
electric field parameters must be optimized. Recently, it was suggested that biphasic high …