Recent advances and perspectives in nucleotide second messenger signaling in bacteria

R Hengge, M Pruteanu, J Stülke, N Tschowri… - Microlife, 2023 - academic.oup.com
Nucleotide second messengers act as intracellular 'secondary'signals that represent
environmental or cellular cues, ie the 'primary'signals. As such, they are linking sensory …

The biofilm community resurfaces: new findings and post-pandemic progress

JL Greenwich, D Fleming, E Banin… - Journal of …, 2023 - Am Soc Microbiol
ABSTRACT The ninth American Society for Microbiology Conference on Biofilms was
convened in-person on 13–17 November 2022 in Charlotte, NC. As the first of these …

A deterministic, c-di-GMP-dependent program ensures the generation of phenotypically similar, symmetric daughter cells during cytokinesis

M Pérez-Burgos, M Herfurth, A Kaczmarczyk… - Nature …, 2024 - nature.com
Phenotypic heterogeneity in bacteria can result from stochastic processes or deterministic
programs. The deterministic programs often involve the versatile second messenger c-di …

Binding of GTP to BifA is required for the production of Pel-dependent biofilms in Pseudomonas aeruginosa

JC Van Loon, GB Whitfield, N Wong… - Journal of …, 2024 - Am Soc Microbiol
The Pel exopolysaccharide is one of the most mechanistically conserved and
phylogenetically diverse bacterial biofilm matrix determinants. Pel is a major contributor to …

Unveiling a virulence-regulating mechanism in Aeromonas hydrophila: a quantitative exoproteomic analysis of an AraC-like protein

L Zhang, L Sun, R Srinivasan, M Lin, L Gong… - Frontiers in …, 2023 - frontiersin.org
Bacterial AraC is a transcription factor family that initiates transcription by recruiting RNA
polymerase to the promoter and directly regulating various bacterial phenotypes. It also …

The global regulation of c‐di‐GMP and cAMP in bacteria

C Liu, R Shi, MS Jensen, J Zhu, J Liu, X Liu, D Sun… - Mlife, 2024 - Wiley Online Library
Nucleotide second messengers are highly versatile signaling molecules that regulate a
variety of key biological processes in bacteria. The best‐studied examples are cyclic AMP …

Identification of a CTX-M-255 β-lactamase containing a G239S substitution selectively conferring resistance to penicillin/β-lactamase inhibitor combinations

MR Andreasen, T Rick… - Journal of …, 2024 - academic.oup.com
Abstract Objectives An Escherichia coli isolate, WGS1363, showed resistance to piperacillin/
tazobactam but susceptibility to cephalosporins and contained a previously unrecognized β …

A deterministic, c-di-GMP-dependent genetic program ensures the generation of phenotypically similar, symmetric daughter cells during cytokinesis

M Perez-Burgos, M Herfurth, A Kaczmarczyk, A Harms… - bioRxiv, 2024 - biorxiv.org
Phenotypic heterogeneity in bacteria results from stochastic processes or deterministic
genetic programs. These deterministic programs often incorporate the versatile second …

The regulation of polar flagella assembly in Pseudomonas putida

M Pulido-Sánchez, A Leal-Morales, A López-Sánchez… - bioRxiv, 2023 - biorxiv.org
ABSTRACT The Gram-negative bacterium Pseudomonas putida bears a tuft of flagella at a
single cell pole. New flagella must be assembled de novo every cell cycle to secure motility …

Polarity of c-di-GMP synthesis and degradation

V Kreiling, KM Thormann - Microlife, 2023 - academic.oup.com
The bacterial cell pole has long been recognized as a defined compartment for enzymatic
activities that are important or even vital for the cell. Polarity of diguanylate cyclases and …