Since its development about 40 years ago (1981–2021), Morris water maze has turned into
a very popular tool for assessing spatial learning and memory. Its many advantages have …

Pesticides are widely-used chemicals commonly applied in agriculture for the protection of
crops from pests. Depending on the class of pesticides, the specific substances may have a …

Status epilepticus (SE), a medical emergency that is typically terminated through
antiepileptic drug treatment, leads to hippocampus dysfunction typified by …

Ethologically relevant behavioral testing is a critical component of any study that uses
mouse models to study the cognitive effects of various physiological or pathological …

Background Gut homeostasis, including intestinal immunity and microbiome, is essential for
cognitive function via the gut-brain axis. This axis is altered in high-fat diet (HFD)-induced …

Persistent cognitive and mood dysfunction is the primary CNS symptom in veterans afflicted
with Gulf War Illness (GWI). This study investigated the efficacy of melatonin (MEL) for …

Dendrobium officinale polysaccharide (DOP) has received an increasing amount of attention
as it could alleviate AD-related cognitive impairment via the regulation of microglial …

Abstract Lipocalin‐2 (LCN2) has diverse functions in multiple pathophysiological conditions;
however, its pathogenic role in vascular dementia (VaD) is unknown. Here, we investigated …

Background “Western” style dietary patterns are characterized by a high proportion of highly
processed foods rich in fat and low in fiber. This diet pattern is associated with a myriad of …

Medial ganglionic eminence (MGE)-like interneuron precursors derived from human
induced pluripotent stem cells (hiPSCs) are ideal for developing patient-specific cell therapy …