Congenital athymia is an ultra-rare disease characterized by the absence of a functioning
thymus. It is associated with several genetic and syndromic disorders including FOXN1 …

Combined Immunodeficiencies (CID) are rare congenital disorders characterized by
defective T-cell development that may be associated with B-and NK-cell deficiency. They are …

The main function of the thymus is to support the establishment of a wide repertoire of T
lymphocytes capable of eliminating foreign pathogens, yet tolerant to self‐antigens …

As the primary site for T cell development, the thymus is responsible for the production and
selection of a functional, yet self-tolerant T cell repertoire. This critically depends on thymic …

Simple Summary Teleost fish, the most abundant group of vertebrates, represent an
excellent tool to establish possible correlations between the histological organization of their …

Congenital heart defects occur in almost 80% of patients with CHARGE syndrome, a
sporadically occurring disease causing craniofacial and other abnormalities due to …

Nitazoxanide (NTZ) is a broad-spectrum immunomodulatory drug, and little information is
about the immunotoxicity of aquatic organisms induced by NTZ. In the present study …

Mutations in the chromatin remodeller‐coding gene CHD7 cause CHARGE syndrome (CS).
CS features include moderate to severe neurological and behavioural problems, clinically …

The development of the vertebrate visual system involves complex morphogenetic
interactions of cells derived from multiple embryonic lineages. Disruptions in this process …

Prenatal alcohol exposure (PAE) can have immediate and long-lasting toxic and teratogenic
effects on an individual's development and health. As a toxicant, alcohol can lead to a …