Biosynthesis, evolution and ecology of microbial terpenoids

M Avalos, P Garbeva, L Vader, GP van Wezel… - Natural Product …, 2022 - pubs.rsc.org
Covering: through June 2021 Terpenoids are the largest class of natural products
recognised to date. While mostly known to humans as bioactive plant metabolites and part of …

Relevance of earth-bound extremophiles in the search for extraterrestrial life

L Carré, G Zaccai, X Delfosse, E Girard, B Franzetti - Astrobiology, 2022 - liebertpub.com
The recent discovery of extrasolar Earth-like planets that orbit in their habitable zone of their
system, and the latest clues of the presence of liquid water in the subsurface of Mars and in …

Comparative molecular dynamics simulation studies of realistic eukaryotic, prokaryotic, and archaeal membranes

ID Pogozheva, GA Armstrong, L Kong… - Journal of chemical …, 2022 - ACS Publications
We present a comparative all-atom molecular dynamics simulation study of 18
biomembrane systems with lipid compositions corresponding to eukaryotic, bacterial, and …

Evolution of bacterial steroid biosynthesis and its impact on eukaryogenesis

Y Hoshino, EA Gaucher - Proceedings of the National …, 2021 - National Acad Sciences
Steroids are components of the eukaryotic cellular membrane and have indispensable roles
in the process of eukaryotic endocytosis by regulating membrane fluidity and permeability. In …

Physiological Responses of Methanosarcina barkeri under Ammonia Stress at the Molecular Level: The Unignorable Lipid Reprogramming

C Liu, X Zhang, C Chen, Y Yin, G Zhao… - … Science & Technology, 2023 - ACS Publications
Acetotrophic methanogens' dysfunction in anaerobic digestion under ammonia pressure has
been widely concerned. Lipids, the main cytomembrane structural biomolecules, normally …

Lipidomic chemotaxonomy aligned with phylogeny of Halobacteria

W Yao, W Zhang, W He, W Xiao, Y Chen… - Frontiers in …, 2023 - frontiersin.org
Archaea play an important role in global biogeochemical cycles and are considered
ancestral to eukaryotes. The unique lipid composition of archaea, characterized by …

Heat stress dictates microbial lipid composition along a thermal gradient in marine sediments

M Sollich, MY Yoshinaga, S Häusler, RE Price… - Frontiers in …, 2017 - frontiersin.org
Temperature exerts a first-order control on microbial populations, which constantly adjust the
fluidity and permeability of their cell membrane lipids to minimize loss of energy by ion …

New insights into the polar lipid composition of extremely halo (alkali) philic euryarchaea from hypersaline lakes

NJ Bale, DY Sorokin, EC Hopmans, M Koenen… - Frontiers in …, 2019 - frontiersin.org
We analyzed the polar membrane lipids of 13 strains of halo (alkali) philic euryarchaea from
hypersaline lakes. Nine belong to the class Halobacteria, representing two functional …

Up-regulation of the Nrf2/HO-1 antioxidant pathway in macrophages by an extract from a new halophilic archaea isolated in Odiel Saltworks

J Ávila-Román, P Gómez-Villegas, CCCR de Carvalho… - Antioxidants, 2023 - mdpi.com
The production of reactive oxygen species (ROS) plays an important role in the progression
of many inflammatory diseases. The search for antioxidants with the ability for scavenging …

In search for the membrane regulators of archaea

M Salvador-Castell, M Tourte, PM Oger - International journal of …, 2019 - mdpi.com
Membrane regulators such as sterols and hopanoids play a major role in the physiological
and physicochemical adaptation of the different plasmic membranes in Eukarya and …