• The specific situation of the patient. Unless otherwise provided for by national regulations,
off-label use of medication should be limited to situations where it is in the patient's interest …

The microbiology, epidemiology, diagnostics, and treatment of infective endocarditis (IE)
have changed significantly since the Duke Criteria were published in 1994 and modified in …

Abstract Aims The EURO-ENDO registry aimed to study the management and outcomes of
patients with infective endocarditis (IE). Methods and results Prospective cohort of 3116 …

LRRC4 is a novel relatively specific gene, which displays significant down-regulation in
primary brain tumor biopsies and has the potential to suppress brain tumor growth. In this …

Importance Infective endocarditis occurs in approximately 15 of 100 000 people in the
United States and has increased in incidence. Clinicians must make treatment decisions …

Potential Biases Most studies of IE are affected by selection, survival, and referral bias. They
make it difficult to study the natural history of IE in the general population, because treated …

Background—The diagnosis of infective endocarditis (IE) in prosthetic valves and
intracardiac devices is challenging because both the modified Duke criteria (DC) and …

Echocardiography is one of the most powerful diagnostic and monitoring tools available to
the modern emergency/critical care practitioner. Currently, there is a lack of specific …

Objectives: This study sought to determine the value of 18F-fluorodeoxyglucose positron
emission tomography/computed tomography (18F-FDG PET/CT) for diagnosing prosthetic …

Sensitivity and specificity of the modified Duke criteria for native valve endocarditis are both
suboptimal, at approximately 80%. Diagnostic accuracy for intracardiac prosthetic material …