The amyloid cascade hypothesis is a useful framework for therapeutic development in
Alzheimer's disease (AD). Amyloid b 1-42 (Aβ) has been the main target of experimental …

Research on racial differences in Alzheimer disease (AD) dementia has increased in recent
years. Older African American individuals bear a disproportionate burden of AD and …

Background and Objectives To evaluate whether plasma biomarkers of amyloid
(Aβ42/Aβ40), tau (p-tau181 and p-tau231), and neuroaxonal injury (neurofilament light …

Alzheimer's disease (AD) is the most frequent cause of dementia, where the abnormal
accumulation of beta-amyloid (Aβ) and tau lead to neurodegeneration as well as loss of …

Importance Racial and ethnic groups with higher rates of clinical Alzheimer disease (AD) are
underrepresented in studies of AD biomarkers, including amyloid positron emission …

Social determinants of health are the conditions in which people are born, work, live, and
age and the wider set of forces and systems that shape the conditions of daily life. They …

Background Racial and ethnic minoritized groups are disproportionately at risk for
Alzheimer's Disease (AD), but are not sufficiently recruited in AD neuroimaging research in …

Dementia is becoming increasingly prevalent in Latin America, contrasting with stable or
declining rates in North America and Europe. This scenario places unprecedented clinical …

Importance Differences in cerebrospinal fluid (CSF) tau Alzheimer dementia (AD)
biomarkers by self-identified race have been observed in prior studies. More recently …

Objectives Concentrations of amyloid‐β peptides (Aβ42/Aβ40) and neurofilament light (NfL)
can be measured in plasma or cerebrospinal fluid (CSF) and are associated with …