BACKGROUND AND METHODS: We have reviewed and pooled data from published
studies to evaluate the relationship between microsatellite instability (MSI) and colorectal …

The immensity of genes and molecules implicated in gastric carcinogenesis is
overwhelming and the relevant importance of some of these molecules is too often unclear …

Summary DNA N 6-methyladenine (6mA) modification is the most prevalent DNA
modification in prokaryotes, but whether it exists in human cells and whether it plays a role in …

Voltage-gated calcium channels (VGCCs) comprise five subtypes: The L‑type; R‑type; N‑
type; P/Q‑type; and T‑type, which are encoded by α1 subunit genes. Calcium ion channels …

Purpose: Gastric cancer may be subdivided into 3 distinct subtypes—proximal, diffuse, and
distal gastric cancer—based on histopathologic and anatomic criteria. Each subtype is …

Background & Aims Little is known about factors that promote gastric carcinogenesis. We
analyzed multiple microarray data sets for messenger RNAs (mRNAs) that were increased …

The cellular phenotype is described by a complex network of molecular interactions.
Elucidating network properties that distinguish disease from the healthy cellular state is …

TGF-β is a multifunctional cytokine affecting many cell types and implicated in tissue
remodeling processes. Due to its many functions and cell-specific effects, the consequences …

Collagen VI is significant in the progression of numerous types of cancer. Type VI collagen
consists of three α‑chains and collagen VI α3 (COL6A3) encodes the α3 chain. The …

The DNA repair pathways help to maintain genomic integrity and therefore genetic variation
in the pathways could affect the propensity to develop cancer. Selected germline single …