Covid‐19 and dengue: double punches for dengue‐endemic countries in Asia
Summary The coronavirus disease 2019 (Covid‐19) pandemic, caused by severe acute
respiratory syndrome coronavirus 2 (SARS‐CoV‐2), is an international public health crisis …
respiratory syndrome coronavirus 2 (SARS‐CoV‐2), is an international public health crisis …
Innate immune receptors in platelets and platelet-leukocyte interactions
PRB Dib, AC Quirino-Teixeira, LB Merij… - Journal of Leucocyte …, 2020 - academic.oup.com
Platelets are chief cells in hemostasis. Apart from their hemostatic roles, platelets are major
inflammatory effector cells that can influence both innate and adaptive immune responses …
inflammatory effector cells that can influence both innate and adaptive immune responses …
Platelets in immune response to virus and immunopathology of viral infections
Platelets are essential effector cells in hemostasis. Aside from their role in coagulation,
platelets are now recognized as major inflammatory cells with key roles in the innate and …
platelets are now recognized as major inflammatory cells with key roles in the innate and …
Platelets mediate increased endothelium permeability in dengue through NLRP3-inflammasome activation
ED Hottz, JF Lopes, C Freitas… - Blood, The Journal …, 2013 - ashpublications.org
Dengue is the most frequent hemorrhagic viral disease and re-emergent infection in the
world. Although thrombocytopenia is characteristically observed in mild and severe forms of …
world. Although thrombocytopenia is characteristically observed in mild and severe forms of …
Human megakaryocytes possess intrinsic antiviral immunity through regulated induction of IFITM3
Evolving evidence indicates that platelets and megakaryocytes (MKs) have unexpected
activities in inflammation and infection; whether viral infections upregulate biologically …
activities in inflammation and infection; whether viral infections upregulate biologically …
Platelet-TLR7 mediates host survival and platelet count during viral infection in the absence of platelet-dependent thrombosis
M Koupenova, O Vitseva, CR MacKay… - Blood, The Journal …, 2014 - ashpublications.org
Viral infections have been associated with reduced platelet counts, the biological
significance of which has remained elusive. Here, we show that infection with …
significance of which has remained elusive. Here, we show that infection with …
[HTML][HTML] Platelets: essential components of the immune system
RA Ali, LM Wuescher, RG Worth - Current trends in immunology, 2015 - ncbi.nlm.nih.gov
Platelets are anucleate cell fragments known for their central role in coagulation and
vascular integrity. However, it is becoming increasingly clear that platelets contribute to …
vascular integrity. However, it is becoming increasingly clear that platelets contribute to …
[HTML][HTML] The pathology of severe dengue in multiple organs of human fatal cases: histopathology, ultrastructure and virus replication
TF Póvoa, AMB Alves, CAB Oliveira, GJ Nuovo… - PloS one, 2014 - journals.plos.org
Dengue is a public health problem, with several gaps in understanding its pathogenesis.
Studies based on human fatal cases are extremely important and may clarify some of these …
Studies based on human fatal cases are extremely important and may clarify some of these …
Platelets in pulmonary immune responses and inflammatory lung diseases
EA Middleton, AS Weyrich… - Physiological …, 2016 - journals.physiology.org
Platelets are essential for physiological hemostasis and are central in pathological
thrombosis. These are their traditional and best known activities in health and disease. In …
thrombosis. These are their traditional and best known activities in health and disease. In …
Dengue virus binding and replication by platelets
AY Simon, MR Sutherland… - Blood, The Journal of …, 2015 - ashpublications.org
Dengue virus (DENV) infection causes∼ 200 million cases of severe flulike illness annually,
escalating to life-threatening hemorrhagic fever or shock syndrome in∼ 500 000. Although …
escalating to life-threatening hemorrhagic fever or shock syndrome in∼ 500 000. Although …