Hydrazide–hydrazones as potential antimicrobial agents: overview of the literature since 2010

Ł Popiołek - Medicinal Chemistry Research, 2017 - Springer
Hydrazide–hydrazone derivatives are present in many bioactive molecules and display a
wide variety of biological activities, such as antibacterial, antitubercular, antifungal …

[PDF][PDF] A systematic review on the synthesis and biological activity of hydrazide derivatives

MS Khan, SP Siddiqui, N Tarannum - Hygeia. J. Drugs Med, 2017 - hygeiajournal.com
Plan: A systematic review on the synthesis and biological activity of hydrazides and their
derivatives. Preface: The chemistry of hydrazide and its derivatives has obtained great …

Design and synthesis of novel (S)-Naproxen hydrazide-hydrazones as potent VEGFR-2 inhibitors and their evaluation in vitro/in vivo breast cancer models

MI Han, P Atalay, CÜ Tunç, G Ünal, S Dayan… - Bioorganic & Medicinal …, 2021 - Elsevier
Naproxen is a common non-steroidal anti-inflammatory drug, which is the most usually used
propionic acid derivative for the treatment of many types of diseases. In this study, a series of …

Antioxidant activity of novel imidazo [2, 1-b] thiazole derivatives: Design, synthesis, biological evaluation, molecular docking study and in silico ADME prediction

ED Dincel, E Gürsoy, T Yilmaz-Ozden… - Bioorganic …, 2020 - Elsevier
A series of novel oxo-hydrazone and spirocondensed-thiazolidine derivatives of imidazo [2,
1-b] thiazole were synthesized and evaluated for their antioxidant activity. The antioxidant …

Binuclear Cu (II), Ni (II) and Zn (II) complexes of hydrazone Schiff bases: Synthesis, spectroscopy, DFT calculations, and SOD mimetic activity

A Zengin, K Serbest, M Emirik, M Özil… - Journal of Molecular …, 2023 - Elsevier
Two new salicylaldimine-based N-heterocyclic hydrazone ligands, N'-[(2-hydroxyphenyl)
methylene]-2-(2-phenyl-1H-benzimidazol-1-yl) acetohydrazone (H 2 L 1) and 2-[2-(3 …

Design and synthesis of novel Imidazo [2, 1-b] thiazole derivatives as potent antiviral and antimycobacterial agents

E Gürsoy, ED Dincel, L Naesens, NU Güzeldemirci - Bioorganic chemistry, 2020 - Elsevier
A series of novel acyl-hydrazone (4a-d) and spirothiazolidinone (5a-d, 6a-d) derivatives of
imidazo [2, 1-b] thiazole were synthesized and evaluated for their antiviral and …

Novel N-Acyl Hydrazone Compounds as Promising Anticancer Agents: Synthesis and Molecular Docking Studies

Y Biliz, B Hasdemir, H Başpınar Küçük… - ACS …, 2023 - ACS Publications
In this study, a new series of N-acyl hydrazones 7a-e, 8a-e, and 9a-e, starting from methyl δ-
oxo pentanoate with different substituted groups 1a-e, were synthesized as anticancer …

Synthesis and anticancer activity of novel hydrazone linkage-based aryl sulfonate derivatives as apoptosis inducers

S Şenkardeş, M İhsan Han, M Gürboğa… - Medicinal Chemistry …, 2022 - Springer
In the present study, the various 28 hybrid molecules containing hydrazone and sulfonate
moieties were synthesized and characterized by FTIR, 1H-NMR, 13C-NMR spectroscopy …

Synthesis, molecular docking and evaluation of novel sulfonyl hydrazones as anticancer agents and COX-2 inhibitors

S Şenkardeş, Mİ Han, N Kulabaş, M Abbak, Ö Çevik… - Molecular …, 2020 - Springer
In trying to develop new anticancer agents, a series of sulfonylhydrazones were
synthesized. All synthesized compounds were checked for identity and purity using …

Synthesis, molecular modeling, in vivo study, and anticancer activity of 1,2,4‐triazole containing hydrazide–hydrazones derived from (S)‐naproxen

Mİ Han, H Bekçi, AI Uba, Y Yıldırım… - Archiv der …, 2019 - Wiley Online Library
Abstract A new series of 1, 2, 4‐triazole containing hydrazide–hydrazones derived from (S)‐
naproxen (7a–m) was synthesized in this study. The structures of these compounds were …