The health of children conceived by ART:'the chicken or the egg?'

S Berntsen, V Söderström-Anttila… - Human reproduction …, 2019 - academic.oup.com
Worldwide, more than 7 million children have now been born after ART: these delivery rates
are steadily rising and now comprise 2–6% of births in the European countries. To achieve …

Intracytoplasmic sperm injection for male infertility and consequences for offspring

SC Esteves, M Roque, G Bedoschi, T Haahr… - Nature Reviews …, 2018 - nature.com
Intracytoplasmic sperm injection (ICSI) has become the most commonly used method of
fertilization in assisted reproductive technology. The primary reasons for its popularity stem …

Etiology of acute leukemia: A review

CK Tebbi - Cancers, 2021 - mdpi.com
Simple Summary Acute leukemias are some of the most common cancers affecting all age
groups. Despite a significant improvement made in the treatment of acute leukemias, their …

Cancer in children born after frozen-thawed embryo transfer: a cohort study

N Sargisian, B Lannering, M Petzold, S Opdahl… - PLoS …, 2022 - journals.plos.org
Background The aim was to investigate whether children born after assisted reproduction
technology (ART), particularly after frozen-thawed embryo transfer (FET), are at higher risk of …

DNA methylation signatures in cord blood of ICSI children

N El Hajj, L Haertle, M Dittrich, S Denk… - Human …, 2017 - academic.oup.com
Abstract STUDY QUESTION Does ICSI induce specific DNA methylation changes in the
resulting offspring? SUMMARY ANSWER Although several thousand analyzed CpG sites …

Risk of cancer in children and young adults conceived by assisted reproductive technology

M Spaan, AW van den Belt-Dusebout… - Human …, 2019 - academic.oup.com
STUDY QUESTION Do children conceived by ART have an increased risk of cancer?
SUMMARY ANSWER Overall, ART-conceived children do not appear to have an increased …

Parental age and childhood cancer risk: A Danish population-based registry study

ZA Contreras, J Hansen, B Ritz, J Olsen, F Yu… - Cancer …, 2017 - Elsevier
Background Though the association between parental age at child's birth and the risk of
childhood cancer has been previously investigated, the evidence to date is inconclusive and …

Fertility treatments and pediatric neoplasms of the offspring: results of a population-based cohort with a median follow-up of 10 years

T Wainstock, A Walfisch, I Shoham-Vardi, I Segal… - American Journal of …, 2017 - Elsevier
Objective Studies have questioned the long-term health effects of offspring conceived after
fertility treatments. Methods We aimed to evaluate whether an association exists between …

Medically Assisted Reproduction and Risk of Cancer Among Offspring

P Rios, P Herlemont, P Fauque, B Lacour… - JAMA Network …, 2024 - jamanetwork.com
Importance Cancer is a leading cause of death among children worldwide. Treatments used
for medically assisted reproduction (MAR) are suspected risk factors because of their …

Polygenic embryo screening: are there potential maternal and fetal harms?

P Ginod, MH Dahan - Reproductive BioMedicine Online, 2023 - Elsevier
Polygenic embryo screening (PES) and its derivate the Embryo Health Score (EHS) has
generated interest in both infertile and fertile populations due to its potential ability to select …