Both inflammasomes and autophagy have important roles in the intracellular homeostasis,
inflammation, and pathology; the dysregulation of these processes is often associated with …

Differentiated thyroid cancers are more frequent in women than in men. These different
frequencies may depend on differences in patient's behavior and in thyroid investigations …

Menstruation occurs in few species and involves a cyclic process of proliferation, breakdown
and regeneration under the control of ovarian hormones. Knowledge of normal endometrial …

The molecular mechanisms underlying the development of thyroid cancer (TC) have been
examined through extensive experiments. A large number of studies have shown that the …

The mammalian Ccr4–Not complex, carbon catabolite repression 4 (Ccr4)-negative on
TATA-less (Not), is a large, highly conserved, multifunctional assembly of proteins that acts …

Estrogen receptor β (ERβ) plays critical roles in thyroid cancer progression. However, its role
in thyroid cancer stem cell maintenance remains elusive. Here, we report that ERβ is …

The orphan nuclear receptor ESRRA (estrogen-related receptor α) is a key regulator of
energy homeostasis and mitochondrial function. Macroautophagy/autophagy, an …

There are about half of papillary thyroid carcinoma (PTC) patients with the experience of
central lymph node metastasis (CLNM), while the model to predict high-risk groups of CLNM …

Leptin, a hormone primarily derived from adipose tissue, is known to induce tumor growth,
but its underlying mechanisms of action are not clearly understood. Inflammasomes, acting …

17β-Estradiol (E2) exerts protective effects on right ventricular (RV) function in pulmonary
arterial hypertension (PAH). Since acute exercise-induced increases in afterload may lead …