Proper localization of membrane proteins is essential for the function of biological
membranes and for the establishment of organelle identity within a cell. Molecular …

Looking at the variety of the thousands of different polypeptides that have been focused on
in the research on the endoplasmic reticulum from the last five decades taught us one …

A complete characterization of the proteome of seminal plasma (SP) is an essential step to
understand how SP influences sperm function and fertility after artificial insemination (AI) …

To infect cells, polyomavirus (PyV) traffics from the cell surface to the endoplasmic reticulum
(ER) where it hijacks elements of the ER-associated degradation (ERAD) machinery to …

Membrane penetration by nonenveloped viruses remains enigmatic. In the case of the
nonenveloped polyomavirus simian virus 40 (SV40), the virus penetrates the endoplasmic …

SGTA is a co-chaperone that, in collaboration with the complex of BAG6/UBL4A/TRC35,
facilitates the biogenesis and quality control of hydrophobic proteins, protecting them from …

Among the realm of repeat containing proteins that commonly serve as “scaffolds” promoting
protein-protein interactions, there is a family of proteins containing between 2 and 20 …

Small glutamine-rich tetratricopeptide repeat-containing protein 2 (Sgt2) is a multi-module
co-chaperone involved in several protein quality control pathways. The TPR domain of Sgt2 …

Abstract The Pearl River Estuary (PRE) is the largest estuary in southern China and under
high metal stress. In the present study, we employed an integrated method of transcriptomics …

Low birthweight and reduced height gain during infancy (stunting) may arise at least in part
from adverse early life environments that trigger epigenetic reprogramming that may favor …