[HTML][HTML] ABC transporters affects tumor immune microenvironment to regulate cancer immunotherapy and multidrug resistance

J Fan, KKW To, ZS Chen, L Fu - Drug Resistance Updates, 2023 - Elsevier
Multidrug resistance (MDR) is the phenomenon in which cancer cells simultaneously
develop resistance to a broad spectrum of structurally and mechanistically unrelated drugs …

Auxin and its role in plant development: structure, signalling, regulation and response mechanisms

GLB Gomes, KC Scortecci - Plant Biology, 2021 - Wiley Online Library
Auxins are plant hormones that play a central role in controlling plant growth and
development across different environmental conditions. Even at low concentrations, auxins …

Physiological and molecular mechanisms of medicinal plants in response to cadmium stress: Current status and future perspective

P Fan, L Wu, Q Wang, Y Wang, H Luo, J Song… - Journal of Hazardous …, 2023 - Elsevier
Medicinal plants have a wide range of uses worldwide. However, the quality of medicinal
plants is affected by severe cadmium pollution. Cadmium can reduce photosynthetic …

[HTML][HTML] Factors influencing the blood-brain barrier permeability

Y Zhao, L Gan, L Ren, Y Lin, C Ma, X Lin - Brain research, 2022 - Elsevier
The blood-brain barrier (BBB) is a dynamic structure that protects the brain from harmful
blood-borne, endogenous and exogenous substances and maintains the homeostatic …

Molecular structure of the human CFTR ion channel

F Liu, Z Zhang, L Csanády, DC Gadsby, J Chen - Cell, 2017 - cell.com
The cystic fibrosis transmembrane conductance regulator (CFTR) is an ATP-binding
cassette (ABC) transporter that uniquely functions as an ion channel. Here, we present a 3.9 …

ABC transporter-mediated multidrug-resistant cancer

H Amawi, HM Sim, AK Tiwari, SV Ambudkar… - Drug transporters in …, 2019 - Springer
ATP-binding cassette (ABC) transporters are involved in active pumping of many diverse
substrates through the cellular membrane. The transport mediated by these proteins …

Current understanding of modes of action of multicomponent bioactive phytochemicals: Potential for nutraceuticals and antimicrobials

M Wink - Annual Review of Food Science and Technology, 2022 - annualreviews.org
Plants produce a diversity of plant secondary metabolites (PSMs), which function as defense
chemicals against herbivores and microorganisms but also as signal compounds. An …

Dissection of the antibacterial mechanism of zinc oxide nanoparticles with manipulable nanoscale morphologies

X Zhu, J Wang, L Cai, Y Wu, M Ji, H Jiang… - Journal of hazardous …, 2022 - Elsevier
Despite the extensive uses of ZnO nanoparticles as promising antimicrobial agents to tackle
the severe microbial infections, the systematic antibacterial studies on ZnO nanoparticles …

Role of ATP‐binding cassette transporters in maintaining plant homeostasis under abiotic and biotic stresses

A Dahuja, RR Kumar, A Sakhare, A Watts… - Physiologia …, 2021 - Wiley Online Library
The ATP‐binding cassette (ABC) transporters belong to a large protein family predominantly
present in diverse species. ABC transporters are driven by ATP hydrolysis and can act as …

[HTML][HTML] Atomic structure of the cystic fibrosis transmembrane conductance regulator

Z Zhang, J Chen - Cell, 2016 - cell.com
The cystic fibrosis transmembrane conductance regulator (CFTR) is an anion channel
evolved from the ATP-binding cassette (ABC) transporter family. In this study, we determined …