BK channels in the central nervous system
Large conductance Ca 2+-and voltage-activated K+(BK) channels are widely distributed in
the postnatal central nervous system (CNS). BK channels play a pleiotropic role in …
the postnatal central nervous system (CNS). BK channels play a pleiotropic role in …
TRPC6 channels and their binding partners in podocytes: role in glomerular filtration and pathophysiology
Loss or dysfunction of podocytes is a major cause of glomerular kidney disease. Several
genetic forms of glomerular disease are caused by mutations in genes that encode structural …
genetic forms of glomerular disease are caused by mutations in genes that encode structural …
[HTML][HTML] Large conductance, Ca2+-activated K+ channels (BKCa) and arteriolar myogenic signaling
Myogenic, or pressure-induced, vasoconstriction is critical for local blood flow
autoregulation. Underlying this vascular smooth muscle (VSM) response are events …
autoregulation. Underlying this vascular smooth muscle (VSM) response are events …
Modulation of BK channel function by auxiliary beta and gamma subunits
Q Li, J Yan - International review of neurobiology, 2016 - Elsevier
Abstract The large-conductance, Ca 2+-and voltage-activated K+(BK) channel is
ubiquitously expressed in mammalian tissues and displays diverse biophysical or …
ubiquitously expressed in mammalian tissues and displays diverse biophysical or …
Big Potassium (BK) ion channels in biology, disease and possible targets for cancer immunotherapy
L Ge, NT Hoa, Z Wilson, G Arismendi-Morillo… - International …, 2014 - Elsevier
Abstract The Big Potassium (BK) ion channel is commonly known by a variety of names
(Maxi-K, KCNMA1, slo, stretch-activated potassium channel, KCa1. 1). Each name reflects a …
(Maxi-K, KCNMA1, slo, stretch-activated potassium channel, KCa1. 1). Each name reflects a …
Low voltage activation of KCa1. 1 current by Cav3-KCa1. 1 complexes
R Rehak, TM Bartoletti, JDT Engbers, G Berecki… - PloS one, 2013 - journals.plos.org
Calcium-activated potassium channels of the KCa1. 1 class are known to regulate
repolarization of action potential discharge through a molecular association with high …
repolarization of action potential discharge through a molecular association with high …
Functional insights into modulation of BKCa channel activity to alter myometrial contractility
The large-conductance voltage-and Ca2+-activated K+ channel (BKCa) is an important
regulator of membrane excitability in a wide variety of cells and tissues. In myometrial …
regulator of membrane excitability in a wide variety of cells and tissues. In myometrial …
WNK1 activates large-conductance Ca2+-activated K+ channels through modulation of ERK1/2 signaling
Y Liu, X Song, Y Shi, Z Shi, W Niu, X Feng… - Journal of the …, 2015 - journals.lww.com
With no lysine (WNK) kinases are members of the serine/threonine kinase family. We
previously showed that WNK4 inhibits renal large-conductance Ca 2+-activated K+(BK) …
previously showed that WNK4 inhibits renal large-conductance Ca 2+-activated K+(BK) …
Exercise training attenuates ageing‐induced BKCa channel downregulation in rat coronary arteries
S Albarwani, S Al‐Siyabi, H Baomar… - Experimental …, 2010 - Wiley Online Library
Physical inactivity and ageing are widely recognized as risk factors for development of
coronary artery disease. One of the characteristic changes that occurs in aged coronary …
coronary artery disease. One of the characteristic changes that occurs in aged coronary …
AF17 competes with AF9 for binding to Dot1a to up-regulate transcription of epithelial Na+ channel α
MR Reisenauer, M Anderson, L Huang, Z Zhang… - Journal of Biological …, 2009 - ASBMB
We previously reported that Dot1a· AF9 complex represses transcription of the epithelial
Na+ channel subunit α (α-ENaC) gene in mouse inner medullary collecting duct mIMCD3 …
Na+ channel subunit α (α-ENaC) gene in mouse inner medullary collecting duct mIMCD3 …