Real-time PCR applications for diagnosis of leishmaniasis

L Galluzzi, M Ceccarelli, A Diotallevi, M Menotta… - Parasites & vectors, 2018 - Springer
Leishmaniasis is a vector-borne disease caused by many Leishmania species, which can
infect both humans and other mammals. Leishmaniasis is a complex disease, with …

Pathologic Mechanisms Underlying the Clinical Findings in Canine Leishmaniosis due to Leishmaniainfantum/chagasi

AF Koutinas, CK Koutinas - Veterinary Pathology, 2014 - journals.sagepub.com
In dogs with symptomatic or asymptomatic leishmaniosis, Leishmania infantum appears to
induce a mixed Th1/Th2 immune response that in the sick dog may eventually result in …

Molecular diagnosis of visceral leishmaniasis

S Sundar, OP Singh - Molecular diagnosis & therapy, 2018 - Springer
Visceral leishmaniasis (VL), a deadly parasitic disease, is a major public health concern
globally. Countries affected by VL have signed the London Declaration on Neglected …

Biomarkers Associated With Leishmania infantum Exposure, Infection, and Disease in Dogs

C Maia, L Campino - Frontiers in cellular and infection microbiology, 2018 - frontiersin.org
Canine leishmaniosis (CanL) is a vector-borne disease caused by the protozoan
Leishmania (Leishmania) infantum species [syn. L.(L.) infantum chagasi species in the …

Protective immunity against challenge with Leishmania (Leishmania) chagasi in beagle dogs vaccinated with recombinant A2 protein

AP Fernandes, MMS Costa, EAF Coelho… - Vaccine, 2008 - Elsevier
In this study, we investigated in dogs the immunogenicity and protective immunity against
Leishmania (Leishmania) chagasi infection induced by vaccination with a formulation …

Advances in the pathogenesis of canine leishmaniosis: epidemiologic and diagnostic implications

MN Saridomichelakis - Veterinary dermatology, 2009 - Wiley Online Library
Canine leishmaniosis caused by Leishmania infantum (Syn. L. chagasi) is an important
zoonosis with a complex pathogenesis. Parasite transmission occurs via female sandflies …

Heterogeneities in Leishmania infantum Infection: Using Skin Parasite Burdens to Identify Highly Infectious Dogs

O Courtenay, C Carson, L Calvo-Bado… - PLoS neglected …, 2014 - journals.plos.org
Background The relationships between heterogeneities in host infection and infectiousness
(transmission to arthropod vectors) can provide important insights for disease management …

Immunity to Leishmania and the rational search for vaccines against canine leishmaniasis

AB Reis, RC Giunchetti, E Carrillo, OA Martins-Filho… - Trends in …, 2010 - cell.com
The control of infection by Leishmania infantum (syn. Leishmania chagasi) in dogs is
essential to stop the current spread of zoonotic visceral leishmaniasis. The past few years …

Long-term follow-up of dogs with leishmaniosis treated with meglumine antimoniate plus allopurinol versus miltefosine plus allopurinol

L Manna, R Corso, G Galiero, A Cerrone, P Muzj… - Parasites & vectors, 2015 - Springer
Background Visceral leishmaniosis is a potentially life-threatening illness caused by a
protozoan parasite of the genus Leishmania. It is found mainly in areas where both the …

Expression of IFN-γ, TNF-α, IL-10 and TGF-β in lymph nodes associates with parasite load and clinical form of disease in dogs naturally infected with Leishmania …

CF Alves, IFG de Amorim, EP Moura, RR Ribeiro… - Veterinary immunology …, 2009 - Elsevier
American visceral leishmaniasis is a zoonosis of the New World. Dogs are the main
reservoir of the disease and there is much interest in the understanding of mechanisms …