This review focuses on the current knowledge of the effects of thyroid hormones on central
nervous system differentiation and development in animals and the human fetal brain. The …

Aquatic and terrestrial environments are increasingly contaminated by anthropogenic
sources that include pharmaceuticals, personal care products, and industrial and …

Thyroid hormones (THs) play critical roles in profound changes in many vertebrates, notably
in mammalian neurodevelopment, although the precise molecular mechanisms of these …

Abstract 2, 2′, 4, 4′-Tetrabromodiphenyl ether (BDE47) is the most abundant PBDE
congeners in biological samples. It has strong tendencies to bioaccumulate and potentially …

Background: Penta-brominated diphenyl ethers (PentaBDEs) are endocrine-disrupting
chemicals that structurally resemble thyroid hormones and were widely used as flame …

The liver is one of the major targets of hormones, including thyroid hormones (THs), and
many industrial chemicals, such as endocrine-disrupting chemicals. Those compounds may …

Exposures to polybrominated diphenyl ethers (PBDEs) have been shown to alter immune
function in adult organisms across a variety of taxa. However, few if any studies have …

Previous studies have shown that BDE-47, one of the most abundant polybrominated
diphenyl ethers (PBDEs) congeners, has a weak estrogenic activity, but it has remained …

Abstract The effect of 2, 2′, 4, 4′-tetrabromodiphenyl ether (BDE-47), a persistent
environmental pollutant commonly used as a flame retardant in various consumer products …

There is a need for rapidly screening thyroid hormone (TH) signaling disruptors in vivo
considering the essential role of TH signaling in vertebrates. We aimed to establish a rapid …